Transgene Information

NamedvIs75 View on WormBase
Description[myo-3::Abeta 1-42 G37L::3' UTR(long) + mtl-2::GFP)]

Strains carrying this transgene

Strain Genotype Species Description
CL2621 smg-1(cc546) I; dvIs75. C. elegans dvIs75 [myo-3::Abeta 1-42 G37L::3' UTR(long) + mtl-2::GFP)]. Temperature-inducible induction of human Abeta peptide in body wall muscle; paralysis in ~32 hr if induced as L3 larvae. Maintain at 16 C to prevent strong Abeta induction and larval paralysis/arrest. Reference: Fonte V., et al. Mol Neurodegener. 2011 Aug 23;6(1):61.