Transgene Information
| Name | dvIs75 View on WormBase |
|---|---|
| Description | [myo-3::Abeta 1-42 G37L::3' UTR(long) + mtl-2::GFP)] |
Strains carrying this transgene
| Strain | Genotype | Species | Description |
|---|---|---|---|
| CL2621 | smg-1(cc546) I; dvIs75. | C. elegans | dvIs75 [myo-3::Abeta 1-42 G37L::3' UTR(long) + mtl-2::GFP)]. Temperature-inducible induction of human Abeta peptide in body wall muscle; paralysis in ~32 hr if induced as L3 larvae. Maintain at 16 C to prevent strong Abeta induction and larval paralysis/arrest. Reference: Fonte V., et al. Mol Neurodegener. 2011 Aug 23;6(1):61. |