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Strain Species Genotype
CB262 C. elegans unc-37(e262) I. Show Description
Coiler Unc. Severe. Recessive. M-MATING+POOR <1%WT.
NC106 C. elegans unc-37(e262 wd26) I. Show Description
Incompletely-penetrant exploding vulva. wd26 (E580K) is an intragenic revertant of the e262 allele for the backward movement phenotype; it is not known if it also modifies other e262 phenotypes. The wd26 lesion (E580K) is molecularly identical to wd14, wd16, wd17, wd18, etc. Reference: Pflugrad A, et al. Development. 1997 May;124(9):1699-709.
OH9305 C. elegans unc-37(ot240) otIs114 I. Show Description
otIs114 [lim-6p::GFP + rol-6(su1006)]. Rollers. Whole genome sequenced strain.
BW1046 C. elegans unc-37(e262) daf-8(e1393) I. Show Description
Unc. Constitutive dauer formation (Daf-c) at 25C.
BW983 C. elegans bli-4(e937) unc-37(e262) I. Show Description
BliUnc. Blister seen in old adults.
NC37 C. elegans unc-37(wd17) I; unc-4(e2322) II. Show Description
unc-37(wd17) is a dominat suppressor of unc-4(e2322ts). unc-37(wd17) has no phenotype alone.
BC11588 C. elegans dpy-5(e907) I; sIs11330. Show Description
sIs11330 [rCesW02D3.9::GFP + pCeh361]. Maintain by picking WT. WT animals are GFP+. Strain construction supported by Genome British Columbia and Genome Canada. Please acknowledge McKay et al, Cold Spring Harbor Symposia on Quantitative Biology 68: 159-169 2004 (WBPaper00006525).
NC85 C. elegans unc-37(wd17wd22)/dpy-14(e188) I. Show Description
Heterozygotes are WT and segregate WT, Dpys and Steriles.
NC92 C. elegans unc-37(wd17wd20)/dpy-14(e188) I. Show Description
Heterozygotes are WT and segregate WT, Dpys, and Steriles.
NC93 C. elegans unc-37(wd17wd21)/dpy-14(e188) I. Show Description
Heterozygotes are WT and segregate WT, Dpys and Steriles.
KR1406 C. elegans unc-37(h763) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Show Description
BC124 C. elegans dpy-14(e188) unc-13(e51) unc-37(s80)/unc-15(e73) I. Show Description
Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLet. The DpyUncLet larvae are abnormal. Pick WT to maintain.
OH7410 C. elegans unc-37(ot37) otIs114 I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). Show Description
otIs114 [lim-6p::GFP + rol-6(su1006)]. Rollers.
OH4605 C. elegans unc-37(ot59)/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); him-8(e1489) IV; otIs3 V. Show Description
Heterozygotes are WT and GFP+ in the pharynx. ot59 is homozygous inviable. qIs48 is an insertion of ccEx9747 (carries myo-2::GFP, pes-10::GFP, and a gut enhancer fused to GFP) onto the hT2 chromosome and is homozygous lethal. otIs3[lin-15(+) + gcy-7::GFP]. otIs3 is expressed in ASEL in WT animals. In this ot59 strain, otIs3 is expressed in ASEL and ASER.
NC1015 C. elegans unc-119(ed3) III; wdEx457. Show Description
wdEx457 [F39B2.8::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in pharyngeal muscles, posterior ventral cord motor neurons, tail neurons, and a few head neurons. Construct made by M. Vidal lab; candidate unc-37 target gene. F39B2.8 also known as gpr-158.
NC782 C. elegans unc-119(ed3) III; wdEx290. Show Description
wdEx290 [acr-15::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in VNC, head neurons, and tail neurons. Construct made by M. Vidal lab; candidate unc-37 target gene.
NC821 C. elegans unc-119(ed3) III; wdEx329. Show Description
wdEx329 [F09C3.2::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in ventral nerve cord. Construct made by M. Vidal lab; candidate unc-37 target gene.
NC844 C. elegans unc-119(ed3) III; wdEx345. Show Description
wdEx345 [F55C12.4::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in VNC, head neurons, and tail neurons. Construct made by M. Vidal lab; candidate unc-37 target gene.
NC845 C. elegans unc-119(ed3) III; wdEx346. Show Description
wdEx346 [tig-1::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in head neurons, tail neurons. head muscles, and vulva. Construct made by M. Vidal lab; candidate unc-37 target gene.
NC847 C. elegans unc-119(ed3) III; wdEx348. Show Description
wdEx348 [C13G3.1::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in VNC, head neurons, and tail neurons. Construct made by M. Vidal lab; candidate unc-37 target gene.
NC850 C. elegans unc-119(ed3) III; wdEx351. Show Description
wdEx351 [tsp-7::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in motor neurons. Construct made by M. Vidal lab; candidate unc-37 target gene.
NC852 C. elegans unc-119(ed3) III; wdEx353. Show Description
wdEx353 [Y34D9B.1a::GFP + unc-119(+)]. mig-1::GFP construct made by Marc Vidal's group at Harvard as part of the promoterome project; unc-37 target gene. GFP expression observed in all classes of VNC motor neurons, head & tail neurons, body wall muscle, and intestine.
NC902 C. elegans unc-119(ed3) III; wdEx381. Show Description
wdEx381 [F55C12.4::GFP + unc-119(+)]. Pick non-Unc to maintain. GFP expression in VNC, head neurons, and tail neurons. Construct made by M. Vidal lab; candidate unc-37 target gene.
SYS681 C. elegans unc-37(dev218([mNeonGreen::unc-37]) I; ujIs113 II. Show Description
ujIs113 [pie-1p::mCherry::H2B::pie-1 3'UTR + nhr-2p::mCherry::his-24::let-858 3Â’UTR + unc-119(+)] II. mNeonGreen knockin at N-terminus of unc-37 locus. Cellular protein expression pattern during embryogenesis (until bean stage) is available at http://dulab.genetics.ac.cn/TF-atlas. Reference: Ma X, Zhao Z, Xiao L, et al. Nat Methods. 2021;18(8):893-902. doi:10.1038/s41592-021-01216-1.