|SM1366||C. elegans||mxl-2(tm1516) III. Show Description
No observable phenotype.
|SM1480||C. elegans||mxl-2(tm1516) pha-1(e2123) III; him-8(e1489) IV. Show Description
Worms are viable at 15C and dead at 24C.
|SM1508||C. elegans||mxl-2(tm1516) III; bar-1(ga80) X. Show Description
Most defects are similar to bar-1(ga80) single mutant animals [bar-1(ga80) hermaphrodites are usually Egl and often have a protruding vulva (Pvl), although approx. 40% of animals appear WT on plates. Also slightly Unc. In bar-1(ga80) hermaphrodites any of the six vulval precursor cells (P3.p - P8.p) can sometimes fuse with hyp7 without dividing, and P5.p - P7.p can adopt the tertiary cell fate instead of the primary or secondary fates. In addition, the neuroblast QL and its progeny migrate towards the anterior instead of the posterior, and the cell P12 usually adopts the fate of P11. bar-1(ga80) do mate, but poorly. bar-1 encodes a beta-catenin molecule and the ga80 mutation is predicted to cause an early truncation of the protein.] Increased severity of ray 1 displacement.
|SM1584||C. elegans||mxl-2(tm1516) III; plx-1(nc37) IV; him-5(e1490) V; bar-1(ga80) X. Show Description
Hermaphrodites are sluggish and exhibit protruding vulva, ruptured vulva, or internally hatched progeny. Males move slower than WT and have disorganized tail rays.
|SM1586||C. elegans||mxl-2(tm1516) III; plx-1(nc37) IV; him-5(e1490) V. Show Description
Hermaphrodites seem fine. Males have a high penetrance of anterior displacement of ray 1.