More Fields
Strain Species Genotype
MH1019 C. elegans soc-2(ku167) IV. Show Description
No obvious phenotype alone. ku167 suppresses let-60(n1046). Previously called sur-8.
MH1131 C. elegans soc-2(ku167) let-60(n1046) IV. Show Description
Less than 5% Muv. Previously called sur-8(ku167).
MH17 C. elegans sur-2(ku9) I. Show Description
100% bag of worms. Low percentage of dead larvae. Slightly dumpy. ku9 completely suppresses let-60(n1046) Muv phenotype.
MH231 C. elegans let-60(n1046) IV; ksr-1(ku68) X. Show Description
Semi-dominant suppressor of let-60(n1046). Strong reduction of function mutation. At 20C: <1% Muv, 24% Egl, 6% larval lethal, and SM migration defects.
MH2430 C. elegans cbp-1(ku258) III. Show Description
Semidominant suppressor of let-60(n1046).
MH538 C. elegans mek-2(ku114) I; let-60(n1046) IV. Show Description
MH801 C. elegans sur-7(ku119) X. Show Description
No obvious morphological phenotype on its own. Good suppressor of Muv of let-60(n1046).
MT2124 C. elegans let-60(n1046) IV. Show Description
Non-lethal let-60 allele, multivulva phenotype (93% penetrance). Semi-Dominant (17% of hets are Muv). Amber suppressible. Non-null. PKA lin-34. See WBPaper00006902: strain probably carries a side mutation(s) that impairs chemotaxis to the odorant isoamyl alcohol.
MT4244 C. elegans unc-24(e138) let-60(n1046) IV. Show Description
Unc. Muv (sd, gf).
MT4574 C. elegans let-60(n1531)/let-60(n1046) unc-22(e66) IV. Show Description
Heterozygotes are WT and segregate WT, MuvUnc (n1046 e66) and n1531 homozygotes whose phenotypes range from a few dead larva to sterile adults. The normal larval lethality of n1531/n1531 is suppressed by the maternal contribution of n1046. n1046 is semi-dominant.
MT4725 C. elegans let-60(n1046) dpy-20(e1282) IV. Show Description
Dpy (ts). Muv (sd, gf).
MT6378 C. elegans lin-45(n2506) let-60(n1046) IV. Show Description
n2506 suppresses n1046.
MT6399 C. elegans let-60(n1046) IV; cdf-1(n2527) X. Show Description
cdf-1(n2527) suppresses the let-60(n1046gf) Muv phenotype from 95% Muv to <5% Muv. Suppression is weakly semi-dominant.
MT6400 C. elegans let-60(n1046) IV; cgr-1(n2528) X. Show Description
Low penetrance Muv (<5%). Due to variable penetrance larval lethal phenotype at 15C, maintain at 20C.
MT7026 C. elegans mek-2(n2679)/sup-11(n403) dpy-5(e61) I. Show Description
Heterozygotes are WT and segregate WT, steriles with a vulval defect, and scrawny Dpys. n2679 is a suppressor of let-60(n1046) Muv, and is recessive sterile with vulval defects. n267 is an intermediate strength allele. See also WBPaper00002150.
MT8667 C. elegans mek-2(n2678)/sup-11(n403) dpy-5(e61) I. Show Description
Heterozygotes are WT and segregate WT, Sterile Vuls and scrawny Dpys. n2678 is a suppressor of let-60(n1046) Muv. n2678 animals are Vul and recessive sterile. n2678 is a strong allele, probably null. See also WBPaper00002150.
MT8673 C. elegans ksr-1(n2682) X. Show Description
Suppressor of let-60(n1046). Strongest allele. Homozygous viable.
MT8675 C. elegans ksr-1(n2509) X. Show Description
Suppressor of n1046. Weak allele of ksr-1.
MT8677 C. elegans ksr-1(n2526) X. Show Description
Suppressor of n1046. Strong allele.
NH2267 C. elegans let-60(n1046) IV; egl-15(n1454) X. Show Description
Unc and scrawny, but viable. Egl. Class II egl-15 mutation. Lethality suppressed by let-60.
PJ1062 C. elegans let-60(n1046) IV; ccIs55 V. Show Description
ccIs55 [unc-54::lacZ + sup-7(st5)] V.
PS4627 C. elegans let-60&sf1=all">let-60(n1046) unc-31(e169) V/nT1 [let(m435)] (IV;V). Show Description
Maintain by picking WT. Segregates Muv Unc (let-60 unc-31 homozygotes), wild-type heterozygotes and dead eggs. Reference: Moghal N, Sternberg PW. Development. 2003 Jan;130(1):57-69.
PS468 C. elegans let-60(sy100) dpy-20(e1282)/let-60(n1046) unc-22(s7) IV; him-5(e1490) V. Show Description
Heterozygotes are weak Muv and segregate weak Muv, Muv Twitchers, and Dpy Vuls whose progeny are larval lethal. sy100 is a dominant negative allele of let-60. n1046 is a gain-of-function allele of let-60. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
SD366 C. elegans mpk-1(n2521) III; let-60(n1046) IV. Show Description
Less than 5% Muv animals.
WU684 C. elegans let-60(n1046) IV; cgr-1(am114) X. Show Description
Low penetrance Muv (<1%). Slow growing at 20C. 75% larval lethality at 15C. Maintain at 20C.
WU144 C. elegans lin-45(n1924) unc-24(e138) IV. Show Description
Weak lin-45 raf allele: 5% larval lethal. Otherwise, essentially WT vulval induction and fertility. n1924 effectively suppresses the let-60(n1046gf) Muv phenotype. Unc.
WU51 C. elegans lin-45(n2520) unc-24(e138) IV. Show Description
Weak severity of lin-45 raf allele: WT viability, vulval induction and fertility but effectively suppresses the let-60(n1046gf) Muv phenotype. Unc.
WU53 C. elegans lin-45(n1925) unc-24(e138) IV. Show Description
Weak lin-45 raf allele: essentially WT viability, vulval induction and fertility but effectively suppresses the let-60(n1046gf) Muv phenotype. Unc.