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Strain Species Genotype
CB1472 C. elegans mec-6(e1342) I. Show Description
Mechanosensory abnormal. Touch insensitive. Lethargic.
CB2216 C. elegans dpy-5(e61) mec-6(e1342) I. Show Description
Dpy. Mechanosensory Abnormal.
MP84 C. elegans dpy-5(e61) mec-6(lb84) I; unc-8(n491) IV. Show Description
ANR168 C. elegans lin-15B(n744) X; pkIs2386; uIs57. Show Description
pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]. uIs57 [unc-119p::YFP + unc-119p::sid-1 + mec-6p::mec-6]. YFP expression in the muscles. Parkinson's model with hypersensitive neuronal RNAi. Reference: Snow S, et al. (2024). Neuronal CBP-1 is required for enhanced body muscle proteostasis in response to reduced translation downstream of mTOR. Frontiers in Bioscience-Landmark.
MP140 C. elegans enu-2(lb140) III. Show Description
Mildly Unc. Adults display progressive vacuolization of body wall muscle. Neither phenotype is suppressed by mec-6(e1342).
TU3335 C. elegans lin-15B(n744) X; uIs57. Show Description
uIs57 [unc-119p::YFP + unc-119p::sid-1 + mec-6p::mec-6]; appears to map to LG V. Hypersensitive neuronal RNAi by feeding. Superficially wild-type. YFP detectable in neurons. Maintain 15-20 degrees; sick at 25 C. Reference: Calixto et al. (2010) Nature Methods 7:554-9.