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Strain Species Genotype
RB925 C. elegans ire-1(ok799) II. Show Description
C41C4.4. Homozygous. Outer Left Sequence: AGGTAGGCGAGGAGAGATCC. Outer Right Sequence: TAATGGGGTTTCGCTTCTGA. Inner Left Sequence: TCGTCGATGTTCTTCAAACG. Inner Right Sequence: TTCATTCTGGAAGCTTGGCT. Inner Primer WT PCR product: 3031. Deletion size: 2093 bp. Attribution: This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807
RE666 C. elegans ire-1(v33) II. Show Description
Slow growth. Abnormal tail.
SJ30 C. elegans ire-1(zc14) II; zcIs4 V. Show Description
zcIs4 [hsp-4::GFP] V. Animals contain a missense mutation (G739R) in the kinase domain of ire-1. They are unable to induce hsp-4(BiP0 in response to tumincamycin, or heat shock.
ZD1258 C. elegans eif-3.L(qd310) II. Show Description
C17G10.9 Increased lifespan and enhanced resistance to endoplasmic reticulum (ER) stress, independent of IRE-1-XBP-1, ATF-6, and PEK-1. Reference: Cattie DJ, et al. PLoS Genet. 2016 Sep 30;12(9):e1006326.
ZD891 C. elegans agIs219 III; eif-3.K(qd213) V. Show Description
agIs219 [T24B8.5p::GFP::unc-54-3' UTR + ttx-3p::GFP::unc-54-3' UTR] III. T16G1.11 Increased lifespan and enhanced resistance to endoplasmic reticulum (ER) stress, independent of IRE-1-XBP-1, ATF-6, and PEK-1. Reference: Cattie DJ, et al. PLoS Genet. 2016 Sep 30;12(9):e1006326.