Caenorhabditis Genetics Center (CGC)

Rearrangement Information

NamemnDp1 View on WormBase
DescriptionSummary: Translocated duplication, well characterized, does not recombine with normal homologues. Very effective balancer for right portion of LG X from right end through let-4. [Eddy SR] probable left breakpoint in overlap with Y46E3 and Y41C8! Growth conditions: Brood size of reference strain ~235. Unc-3 progeny constitute 25% of total, and about a third of total are slow-growing, sterile duplication homozygotes. by fluorescent in situ hybridization [Eddy SR] mnDp1 is probably internally deleted and missing part of Y52C11 and Y59B2 Handling: Easy to manipulate. Males mate well. mnDp1 is attached to LG V near the left end, and severely reduces recombination frequency from unc-60 to dpy-11. Recommended use: General balancing, strain construction, strain maintenance, mutant screens. [Eddy SR] probable left breakpoint in overlap between Y46E3 and Y41C8! [Eddy SR] mnDp1 is probably internally deleted and missing part of Y59B6 and Y59B2
Genetic positiongenetic position unknown or not listed
Genomic positiongenomic coordinates unknown or not listed

Strains carrying this rearrangement

Strain Genotype Species Description
CGC36 mnDp1 [umnIs25] (X;V)/+ V; unc-3(e151) X. C. elegans umnIs25 [myo-2p::GFP + NeoR, X: 15420938 (intergenic)]. Pick wild-type GFP+ to maintain. Segregates lethals: homozygous Dp/Dp are lethal. Derived by insertion of myo-2p::GFP transgene into mnDp1 duplication in parental strain SP219 using CRISPR/Cas9.
JM144 mnDp1 (X;V)/+ V; lin-15B&lin-15A(n765) gob-1(ca17) X. C. elegans Animals with Dp/+ are WT. Animals which have lost the Dp arrest as L1 with Gob (gut-obstructed) phenotype. Animals with Dp/Dp are sterile homozygotes. gob-1(ca17) is a small deletion, removing nine genes between R03A10.4 and H13N06.4 (inclusive) and possibly the seven additional genes F39D8.2 to R03A10.3 and H13N05.6.
RW1385 mnDp1 (X;V)/+ V; unc-3(e151) pat-9(st558) X. C. elegans Animals with the duplication are WT and segregate WT, sterile and Pats. Strain can be propagated by chunking.
SP219 mnDp1 (X;V)/+ V; unc-3(e151) X. C. elegans Pick wild-type to maintain. Segregates lethals. Dp/Dp are homozygous lethal.
SP223 mnDp1 (X;V)/+ V; unc-3(e151) let-3(mn104) X. C. elegans LETHAL EARLY LARVAL Pick WT to maintain.
SP224 mnDp1 (X;V)/+ V; let-4(mn105) unc-3(e151) X. C. elegans Lethal early larval. Maintain by picking WT.
SP225 mnDp1 (X;V)/+ V; let-5(mn106) unc-3(e151) X. C. elegans LETHAL LATE LARVAL MATERNAL EFFECT Pick WT to maintain.
SP226 mnDp1 (X;V)/+ V; let-9(mn107) unc-3(e151) X. C. elegans Pick WT to maintain. Throws WT, Sterile Uncs, and dead eggs(homozygous Dp).
SP231 mnDp1(X;V)/+ V; unc-3(e151) let-7(mn112) X. C. elegans LETHAL LATE LARVAL SEX-INFLUENCED Maintain by picking WT.
SP232 mnDp1 (X;V)/+ V; unc-3(e151) let-10(mn113) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP233 mnDp1 (X;V)/+ V; unc-3(e151) let-2(mn114) X. C. elegans Pick wild-type to maintain. Segregates wild-type and lethals. mnDp1 duplication rescues unc-3 & let-2. mnDp1 is homozygous lethal.
SP235 mnDp1 (X;V)/+ V; unc-3(e151) let-11(mn116) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP236 mnDp1 (X;V)/+ V; unc-3(e151) let-16(mn117) X. C. elegans FERTILITY POOR LETHAL EARLY LARVAL Maintain by picking WT.
SP238 mnDp1 (X;V)/+ V; unc-3(e151) let-1(mn119) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP239 mnDp1 (X;V)/+ V; unc-3(e151) let-14(mn120) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP240 mnDp1 (X;V)/+ V; unc-3(e151) let-12(mn121) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP241 mnDp1 (X;V)/+ V; unc-3(e151) let-18(mn122) X. C. elegans LETHAL EMBRYONIC. WT strain.
SP244 mnDp1 (X;V)/+ V; unc-3(e151) let-12(mn125) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT. mn125 pka let-17.
SP246 mnDp1 (X;V)/+ V; unc-3(e151) let-15(mn127) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP247 mnDp1 (X;V)/+ V; unc-3(e151) let-33(mn128) X. C. elegans NOT MALE-RESCUED MATERNAL EFFECT STERILE Maintain by picking WT.
SP249 mnDp1 (X;V)/+ V; unc-3(e151) let-6(mn130) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP250 mnDp1 (X;V)/+ V; unc-3(e151) let-2(mn131) X. C. elegans GROWTH SLOW LETHAL EMBRYONIC ts(TEMPERATURE-SENS) See also CGC 1806.
SP253 mnDp1 (X;V)/+ V; unc-3(e151) let-34(mn134) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP254 mnDp1 (X;V)/+ V; unc-3(e151) let-35(mn135) X. C. elegans Maintain by picking WT.
SP257 mnDp1 (X;V)/+ V; unc-3(e151) let-37(mn138) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP259 mnDp1 (X;V)/+ V; unc-3(e151) let-36(mn140) X. C. elegans GROWTH SLOW. MALE-RESCUED. STERILE. Maintain by picking WT.
SP260 mnDp1 (X;V)/+ V; unc-3(e151) let-38(mn141) X. C. elegans STERILE. Maintain by picking WT.
SP261 mnDp1(X;V)/+ V; mnDf2 X. C. elegans WT PHENOTYPE
SP262 mnDp1(X;V)/+ V; mnDf1 X. C. elegans WT Phenotype. Gives dead eggs.
SP265 mnDp1(X;V)/+ V; mnDf4 X. C. elegans WT PHENOTYPE.
SP266 mnDp1(X;V)/+ V; mnDf5 X. C. elegans WT PHENOTYPE. Should throw dead eggs.
SP267 mnDp1(X;V)/+ V; mnDf6 X. C. elegans WT PHENOTYPE. This strain should throw dead eggs, but it is not doing so. Hasn't been checked to see if the deficiency is still there.
SP268 mnDp1(X;V)/+ V; mnDf7 X. C. elegans WT PHENOTYPE. Should throw dead eggs.
SP269 mnDp1(X;V)/+ V; mnDf8 X. C. elegans WT PHENOTYPE.
SP270 mnDp1(X;V)/+ V; mnDf9 X. C. elegans WT PHENOTYPE.
SP271 mnDp1(X;V)/+ V; mnDf10 X. C. elegans WT PHENOTYPE
SP272 mnDp1(X;V)/+ V; mnDf11 X. C. elegans WT PHENOTYPE
SP273 mnDp1(X;V)/+ V; mnDf13 X. C. elegans WT phenotype. Should throw dead eggs.
SP274 mnDp1(X;V)/+ V; mnDf15 X. C. elegans WT PHENOTYPE
SP275 mnDp1(X;V)/+ V; mnDf17 X. C. elegans WT PHENOTYPE
SP276 mnDp1(X;V)/+ V; mnDf18 X. C. elegans WT PHENOTYPE
SP277 mnDp1(X;V)/+ V; mnDf19 X. C. elegans WT PHENOTYPE.
SP278 mnDp1(X;V)/+ V; mnDf20 X. C. elegans WT PHENOTYPE.
SP279 mnDp1(X;V)/+ V; mnDf21 X. C. elegans WT PHENOTYPE
SP374 mnDp1 (X;V)/+ V; unc-3(e151) let-2(mn143) X. C. elegans LETHAL EMBRYONIC RECESSIVE Pick WT to maintain. See also CGC 1806.
SP375 mnDp1 (X;V)/+ V; unc-3(e151) let-39(mn144) X. C. elegans LETHAL EARLY LARVAL. Pick WT to maintain.
SP392 mnDp1 (X;V)/+ V; unc-3(e151) let-41(mn146) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP394 mnDp1(X;V)/+ V; unc-3(e151) mnDf41 X. C. elegans WT PHENOTYPE.
SP395 mnDp1(X;V)/+ V; mnDf42 X. C. elegans WT PHENOTYPE.
SP396 mnDp1 (X;V)/+ V; unc-3(e151) let-40(mn150) X. C. elegans DPYISH. LETHAL EARLY LARVAL AT 25C. STERILE 20C.