Gene Information: tbc-2
| Name | tbc-2 View on WormBase |
|---|---|
| Species | C. elegans |
| Sequence | ZK1248.10 |
| Genetic position | II:-0.90 +/- 0.004 cM |
| Genomic position | II: 5823856..5827443 |
Strains carrying this gene
| Strain | Genotype | Description |
|---|---|---|
| QR15 | tbc-2(tm2241) II. | Large yolk platelets in oocytes. Premature yolk degradation in embryos. Large endosomes in coelomocytes and intestine. Reference: Chotard L, et al. Mol Biol Cell. 2010 Jul 1;21(13):2285-96. |
| QR189 | vhIs12 tbc-2(tm2241) II; unc-119(ed3) III. | vhIs12 [vha-6p::GFP::tbc-2 + Cbr-unc-119(+)] II. vhIs12 is inserted to the left of tbc-2(m2241) in LG II. GFP::TBC-2 rescues the large endosome phenotype in the intestine of tbc-2(tm2241) animals. Outside the intestine, tbc-2(tm2241) animals have large yolk platelets in the oocytes and early embryos that are not rescued. |