Gene Information: dsb-2

Namedsb-2 View on WormBase
Species C. elegans
Genetic positionII:22.97 +/- 0.000 cM
Genomic positionII: 14411095..14412218

Strains carrying this gene

Strain Genotype Description
AV477 dsb-2(me96) II. Age-dependent defect in meiotic double-strand break formation. Homozygous mutants produce elevated frequency of males and dead embryos resulting from defects in meiotic chromosome segregation. The frequency of both males and dead embryos increases in later broods. Reference: Rosu S, et al. PLoS Genet. 2013;9(8):e1003674.
CA1421 meIs8 II; dsb-2(ie58[dsb-2::AID::3xFLAG]) ieSi38 IV. meIs8 [pie-1p::GFP::cosa-1 + unc-119(+)] II. ieSi38 [sun-1p::TIR1::mRuby::sun-1 3'UTR + Cbr-unc-119(+)] IV. Single copy transgene inserted into chromosome IV (cxTi10882) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in germ line and early embryos. This strain can be used for auxin-inducible degradation (AID) in germ line and early embryos. References: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635. Zhang et al., Elife. 2018 Mar 9;7. pii: e30789.