Gene Information: mxl-2

Namemxl-2 View on WormBase
Species C. elegans
Genetic positionIII:-26.93 +/- 0.009 cM
Genomic positionIII: 186949..188131

Strains carrying this gene

Strain Genotype Description
SM1366 mxl-2(tm1516) III. No observable phenotype.
SM1480 mxl-2(tm1516) pha-1(e2123) III; him-8(e1489) IV. Worms are viable at 15C and dead at 24C.
SM1508 mxl-2(tm1516) III; bar-1(ga80) X. Most defects are similar to bar-1(ga80) single mutant animals [bar-1(ga80) hermaphrodites are usually Egl and often have a protruding vulva (Pvl), although approx. 40% of animals appear WT on plates. Also slightly Unc. In bar-1(ga80) hermaphrodites any of the six vulval precursor cells (P3.p - P8.p) can sometimes fuse with hyp7 without dividing, and P5.p - P7.p can adopt the tertiary cell fate instead of the primary or secondary fates. In addition, the neuroblast QL and its progeny migrate towards the anterior instead of the posterior, and the cell P12 usually adopts the fate of P11. bar-1(ga80) do mate, but poorly. bar-1 encodes a beta-catenin molecule and the ga80 mutation is predicted to cause an early truncation of the protein.] Increased severity of ray 1 displacement.
SM1584 mxl-2(tm1516) III; plx-1(nc37) IV; him-5(e1490) V; bar-1(ga80) X. Hermaphrodites are sluggish and exhibit protruding vulva, ruptured vulva, or internally hatched progeny. Males move slower than WT and have disorganized tail rays.
SM1586 mxl-2(tm1516) III; plx-1(nc37) IV; him-5(e1490) V. Hermaphrodites seem fine. Males have a high penetrance of anterior displacement of ray 1.