Caenorhabditis Genetics Center (CGC)

Gene Information: let-49

Namelet-49 View on WormBase
Species C. elegans
SequenceY54E5B.3
Genetic positionI:27.91 +/- 0.092 cM
Genomic positionI: 14820405..14821651

Strains carrying this gene

Strain Genotype Description
RW3199 lev-11(x12) let-49(st44)/lev-11(x12) unc-54(e1152) I. Heterozygotes are Slow Uncs and segregate Slow Uncs, mid-larval lethals and severe Uncs. e1152 is a dominant Unc. let-49 also called med-47. SeeWBPaper00004990.
VC4385 let-49(gk5463[loxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + loxP])/+ I. Apparent homozygous lethal or sterile deletion as unbalanced heterozygote. Deletion of 890 bp with Calarco/Colaiacovo selection cassette conferring myo-2::GFP and G418 resistance inserted at break. Pick viable fertile GFP+ animals to maintain. Left flanking sequence: GGTGCACAAACAGTCAGCCCGTTCCCAAAT. Right flanking sequence: GACGGAGTGCTTCATATGCTTCAGGAGACA. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.