Gene Information: ced-9

Nameced-9 View on WormBase
Species C. elegans
Genetic positionIII:2.36 +/- 0.009 cM
Genomic positionIII: 10335172..10337522

Strains carrying this gene

Strain Genotype Description
KX110 ced-9(n1653) mab-5(mu14) III; bcIs39 V. bcIs39 [lim-7p::ced-1::GFP and lin-15(+)] V.  Temperature sensitive induction of germ cell apoptosis at 25 C. Large number of germ cells are decorated by CED-1::GFP within 48 h. Activates CED-3-mediated cleavage of IFG-1, visualized by western blot (Contreras, V., et al, 2011).
MT11757 ced-9(n3400)/qC1 [dpy-19(e1259) glp-1(q339)] III. Heterozygotes are WT. Segregates Dpy Steriles.
MT3970 mab-5(mu14) ced-9(n1653) III. Temperature sensitive. About 50% HSN missing. Mab confirmed by Hillel Schwartz 12/5/00. Rec'd new stock from Horvitz lab 12/2000. [NOTE: The genotype of this strain was incorrectly described as carrying mab-5(mu114); however, the actual allele is mab-5(mu14).]
MT4770 ced-9(n1950) III. Dominant maternal effect. Survival of cells which normally undergo programmed cell death.
MT5523 unc-69(e587) ced-9(n1950n2161)/qC1 [dpy-19(e1259) glp-1(q339)] III. Heterozygotes are WT and segregate WT, Uncs and DpySte. n2161 is an intragenic revertant of ced-9(n1950). The unc-69 ced-9 homozygotes have a maternal effect lethal phenotype: their offspring arrest as embryos or L1; they also give very few eggs at 25C.
MT7386 ced-9(n2812) III; ced-3(n717) IV. n2812 is a strong loss-of-function allele and a maternal effect lethal.
MT7686 ced-9(n2812)/qC1 [dpy-19(e1259) glp-1(q339)] III. Heterozygotes are WT. Segregates Dpy Steriles.
MT7735 ced-9(n2812) III; ced-3(n2427) IV.
PD9927 ced-9(n2812) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); nIs106 X. nIs106 [lin-11::GFP + lin-15(+)] X. Homozygous maternal effect lethal ced-9 mutation balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP ced-9 homozygotes (maternal effect lethal). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain.