Gene Information: ced-4

Nameced-4 View on WormBase
Species C. elegans
SequenceC35D10.9
Genetic positionIII:-2.42 +/- 0.002 cM
Genomic positionIII: 4852325..4855171

Strains carrying this gene

Strain Genotype Description
IMN34 ced-4(n1162) dpy-17(e164) III; glt-3(bz34) IV; nuIs5 V. nuIs5 [glr-1::GFP + glr-1::G(alpha)s(Q227L) V + lin-15(+)] V. Reference: Tehrani N, et al. (2014) PLoS One 9(11):e113060.
KX89 ced-4(n1162) III; bcIs39 V. bcIs39 [lim-7p::ced-1::GFP and lin-15(+)] V.  Resistant to germ cell apoptosis. No apoptosing germ cells are decorated by CED-1::GFP in the gonad. Genetically identical to KX87 (Contreras, V., et al, 2011).
MT2547 ced-4(n1162) III. Cells that normally die survive. [3/02: A mutation that was not reported (nucleotide 1251 C-> T causing codon 80 ->ochre) was found by Tak Hung. It turns out the mutation was misannotated in the original paper (Development, 1992, 116:309). Bob Horvitz also confirmed the discovery.
MT2550 unc-79(e1068) ced-4(n1162) III. Unc. Cells that normally die survive.
MT2551 ced-4(n1162) dpy-17(e164) III. Dpy. Cells that normally die survive.
MT3315 ced-4(n1416) III; egl-1(n986) V. Absence of cell death. See WBG 10(1):31.
MT5287 ced-4(n1894) III.
MT5816 ced-4(n2273) III. No programmed cell deaths. Weak defects in protection and killing.
MT5851 ced-4(n2274) III.
OH3890 otIs114 I; ced-4(ot188) III. otIs114 [lim-6p::GFP + rol-6(su1006)]. Ectopic expression of otIs114 in the undead sister of ASEL. Rollers.
OH3923 otIs114 I; ced-4(ot228) III. otIs114 [lim-6p::GFP + rol-6(su1006)]. Ectopic expression of otIs114 in the undead sister of ASEL. Rollers.
OH3957 otIs114 I; ced-4(ot248) III. otIs114 [lim-6p::GFP + rol-6(su1006)]. Ectopic expression of otIs114 in the undead sister of ASEL. Rollers.
OH3963 otIs114 I; ced-4(ot238) III. otIs114 [lim-6p::GFP + rol-6(su1006)]. Ectopic expression of otIs114 in the undead sister of ASEL. Rollers.
OH4177 otIs114 I; ced-4(ot248) III. otIs114 [lim-6p::GFP + rol-6(su1006)]. Ectopic expression of otIs114 in the undead sister of ASEL. Rollers.