Gene Information: lin-13

Namelin-13 View on WormBase
Species C. elegans
SequenceC03B8.4
Genetic positionIII:-0.64 +/- 0.003 cM
Genomic positionIII: 7700338..7709491

Strains carrying this gene

Strain Genotype Description
MT1373 lin-13(n387)/unc-32(e189) III; him-5(e1467) V. Hets are WT. At 25C hets segregate WT, Unc, Sterile Muv and males. Maintain by picking WT. ts maternal effect.
MT3025 let-23(n1045) II; lin-13(n387) unc-36(e251)/unc-32(e189) III. Heterozygotes are Vulvaless and segregate more Vul, Vul Unc-36 and Vul Unc-32. n1045 is cold sensitive-strain gives some arrested larvae (L2) which look like little sticks.
MT3061 lin-8(n111) II; sma-3(e491) lin-13(n387) unc-36(e251)/sma-3(e491) lin-37(n758) III. Heterozygotes are Sma. At 25C, hets segregate Sma, SmaMuv (lin-8; sma-3 lin-37), and SmaUncMuvSte (lin-8; sma-3 lin-13 unc-36). At 15C, hets segregate Sma, SmaMuv (lin-8; sma-3 lin-37) and SmaUnc which give sterile F2 (lin-8; sma-3 lin-13 unc-36). n387 is a ts maternal effect mutation.
MT706 lin-13(n388)/unc-32(e189) III. Heterozygotes are WT and segregate WT, Uncs and Sterile Muvs. Maintain by picking WT.
MT8838 lin-13(n770) III. synMuv class B.
OH12343 lin-13(ot785) III; otIs476 V. otIs476 [glr-4p::TagRFP] V. ot785 is a H2121Y missense mutation in the DNA-binding site. De-repression of ectopic effector genes in AS class motor neurons. Reference: Kerk SY, et al. Neuron. 2017 93(1):80-98.
RB951 lin-13(ok838) III. C03B8.4. Homozygous. Outer Left Sequence: TCCTGCATTCGAAGCTCTTT. Outer Right Sequence: ACTCACCCATCGAGTTTTGC. Inner Left Sequence: TTCTACCGTCTTCGTACCCG. Inner Right Sequence: CACCATCACAAGACGGAATG. Inner Primer WT PCR Product: 3097. Deletion size: 1451 bp. Attribution: This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807