Gene Information: tpa-1

Nametpa-1 View on WormBase
Species C. elegans
SequenceB0545.1
Genetic positionIV:-27.00 +/- 0.023 cM
Genomic positionIV: 91980..110819

Strains carrying this gene

Strain Genotype Description
IG339 tpa-1(fr1) frIs7 IV. frIs7 [nlp-29p::GFP + col-12p::DsRed] IV. Displays tpa-1 phenotypes (e.g. resistance to PMA). Isolated in a genetic screen for mutants failing to show an induction of nlp-29p::GFP reporter gene expression upon infection with the fungus Drechmeria coniospora (the Nipi phenotype). References: Pujol N, et al. Curr Biol. 2008 Apr 8;18(7):481-9. Ziegler K, et al. Cell Host Microbe. 2009 Apr 23;5(4):341-52.
IG341 tpa-1(fr3) frIs7 IV. frIs7 [nlp-29p::GFP + col-12p::DsRed] IV. Displays tpa-1 phenotypes (e.g. resistance to PMA). Isolated in a genetic screen for mutants failing to show an induction of nlp-29p::GFP reporter gene expression upon infection with the fungus Drechmeria coniospora (the Nipi phenotype). References: Pujol N, et al. Curr Biol. 2008 Apr 8;18(7):481-9. Ziegler K, et al. Cell Host Microbe. 2009 Apr 23;5(4):341-52.
MJ500 tpa-1(k501) IV. Resistant to tetradecanoyl phorbol acetate. Semi-dominant.
MJ563 tpa-1(k530) IV. Animals grow to be adults with smaller than normal body size and produce a reduced number of progeny on TPA-containing medium. No other apparent phenotypes were so far observed on NGM. Tc1 was originally inserted into a 2.4 kb HindIII genomic fragment. The 1.8 kb portion adjacent to the 3' end of the inserted Tc1 was replaced by an unidentified 1.0 kb fragment probably due to rearrangement during backcrossing.
NL3161 pkIs1330 I; tpa-1(pk1401) dpy-20(e1282) IV. pkIs1330 [hsp::gpa-12QL + dpy-20(+)]. Suppressor of activated G12.
NL4258 pkIs1330 I; tpa-1(pk1585) dpy-20(e1282) IV. pkIs1330 [hsp::gpa-12QL + dpy-20(+)]. Suppressor of activated G12.
PJ1043 tpa-1(k501) IV; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Superficially wild-type. Resistant to PMA.