Gene Information: let-391

Namelet-391 View on WormBase
Species C. elegans
Genetic positionI:0.70 +/- 0.002 cM
Genomic positionI: 6038403..6041267

Strains carrying this gene

Strain Genotype Description
KR350 dpy-5(e61) let-391(h91) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h91 arrests as a late larva or sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
VC510 let-391(ok730) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). C27A12.3. Homozygous lethal or sterile deletion chromosome balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP ok730 homozygotes (variable arrest, from early larval to adult sterile; adults often Dpyish or short with pointed nose). Homozygous hT2[bli-4 let-? qIs48] inviable. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype. Pick WT GFP and check for correct segregation of progeny to maintain. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807