Gene Information: hmp-2

Namehmp-2 View on WormBase
Species C. elegans
SequenceK05C4.6
Genetic positionI:26.59 +/- 0.040 cM
Genomic positionI: 14738882..14742671

Strains carrying this gene

Strain Genotype Description
JJ1068 hmp-2(zu364)/hIn1 [unc-54(h1040)] I. hmp-2(zu364) homozygotes are 99% embryonic or L1 lethal due to a defect in embryonic body elongation; approximately 1% survive to adult stages. Well balanced by hIn1. Maintain by picking WT.
LP316 hmp-2(cp78[GFP::hmp-2a + LoxP]) III. cp78[gfp::hmp-2 + LoxP] III. GFP inserted at the N terminus of endogenous hmp-2 gene by Cas9-triggered homologous recombination. Floxed unc-119 selection cassette was subsequently removed by Cre/Lox recombination leaving a LoxP scar in the second synthetic intron of GFP. Green fluorescence in early embryos, larvae, and adults. Reference: Marston DJ, et al. Curr Biol. 2016 26:2079-2089.
MQ468 hmp-2(qm39) I. Maternally rescued Dpy. Fully zygotically rescued but only partially maternally rescued. Some embryonic lethality and a high degree of larval lethality. Very poor embryonic elongation. Hatchlings are short and deformed. In later stages the anterior half of the body is short but well developed while the posterior is thin.