Gene Information: spn-4

Namespn-4 View on WormBase
Species C. elegans
SequenceZC404.8
Genetic positionV:0.17 +/- 0.018 cM
Genomic positionV: 6783187..6784903

Strains carrying this gene

Strain Genotype Description
DG4158 spn-4(tn1699[spn-4::gfp::3xflag]) V. Apparently wild type
EU370 spn-4(or25) V/nT1 [unc-?(n754) let-?] (IV;V). Heterozygotes are Unc and lay 10/16 dead embryos. spn-4 homozygotes look WT but are non-conditional maternal effect embryonic lethals. Embryos from homozygous mothers exhibit defects in mitotic spindle orientation and cell fate patterning.
EU588 him-8(e1489) IV; spn-4(or191) V. Temperature sensitive. Viable at 15C; lethal at 25C. At 25C, embryos exhibit defects in spindle orientation and cell fate patterning. Throws males.
EU769 spn-4(or25) unc-42(e270) V/nT1 [let-?(m435)] (IV;V). Heterozygotes are WT and lay 10/16 dead eggs. spn-4 unc-42 homozygotes are Unc and lay dead embryos exhibiting defects in mitotic spindle orientation and cell fate patterning. spn-4(or25) homozygotes are non-conditional maternal effect embryonic lethal.
EU772 spn-4(or80) V/nT1 [unc-?(n754) let-?] (IV;V). Heterozygotes are Unc and lay 10/16 dead embryos. spn-4 homozygotes look WT but are non-conditional maternal effect embryonic lethals. Embryos from homozygous mothers exhibit defects in mitotic spindle orientation and cell fate patterning.
EU918 lon-1(e185) par-3(it71)/qC1 [dpy-19(e1259) glp-1(q339)] III; spn-4(or191) V. Temperature sensitive spn-1. Maintain at 15C. Lethal at 25C. Heterozygotes are WT and segregate WT, Lon which give only dead eggs at all temperatures, and Sterile Dpys(ts).
EU923 spn-4(or191) V. Temperature sensitive. Viable at 15C; lethal at 25C. At 25C, embryos exhibit defects in spindle orientation and cell fate patterning.
FX291 +/eT1 III; spn-4(tm291)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36 and dead eggs. 1/3 of WT animals (spn-4 homozygotes) are Mels: segregate only dead embryos with have no morphogenesis. Attribution: This strain was generated by the National Bioresource Project at the Tokyo Women's Medical University School of Medicine, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807