Gene Information: zyg-8

Namezyg-8 View on WormBase
Species C. elegans
Genetic positionIII:14.69 +/- 0.094 cM
Genomic positionIII: 12061713..12072070

Strains carrying this gene

Strain Genotype Description
DH235 zyg-8(b235) III. Temperature sensitive. Egg lethal. Abnormal first cleavage. Maternal effect (m,n).
EU924 zyg-8(or484) III; lin-2(e1309) X. Temperature-sensitive. Maintain at 15C. Reference: Gonczy P, et al. Dev Cell. 2001 Sep;1(3):363-75.
EU931 zyg-8(or490) III; lin-2(e1309) X. Maintain at 15C. Temperature-sensitive embryonic-lethal at restrictive temperature of 26C. Viable embryos at permissive temperature of 15C. Mitotic spindle in one-cell stage embryo assembles normally, but microtubules destabilize at anaphase and spindle becomes mis-positioned toward the posterior pole leading to highly abnormal cleavage and chromosome segregation defects. References: Gonczy P, et al. Dev Cell. 2001 Sep;1(3):363-75. Bellanger JM, et al. J Cell Sci. 2007 Aug 15;120(Pt 16):2963-73.
GE2533 unc-32(e189) zyg-8(t1638)/qC1 [dpy-19(e1259) glp-1(q339)] III; him-3(e1147) IV. Heterozygotes are WT and segregate WT, DpySteriles, and Uncs which give only dead eggs. zyg-8(t1638) pka apo-1(t1638). SeeWBPaper00005199.