Gene Information: egl-15

Nameegl-15 View on WormBase
Species C. elegans
SequenceF58A3.2
Genetic positionX:2.86 +/- 0.003 cM
Genomic positionX: 11016400..11023421

Strains carrying this gene

Strain Genotype Description
DA742 lon-2(e678) unc-6(e78) egl-15(n484) X. Long. Uncoordinated. Egl.
DCR1690 cima-1(wy84) IV; egl-15(n484) wyIs45 X; olaEx1004. wyIs45 [ttx-3p::GFP::rab-3 + unc-122p::RFP] X. olaEx1004 [F25B3.3p::egl-15(5A) + unc-122p::GFP]. Maintain by picking animals with GFP expression in coelomocytes. olaEx1004 does not rescue egl-15(n484) suppression of cima-1 AIY presynaptic defects. Reference: Shao Z, et al. Cell. 2013 Jul 18;154(2):337-50.
DCR1710 cima-1(wy84) IV; egl-15(n484) wyIs45 X; olaEx1015. wyIs45 [ttx-3p::GFP::rab-3 + unc-122p::RFP] X. olaEx1015 [dpy-7p::egl-15(5A) + unc-122p::GFP]. Maintain by picking animals with GFP expression in coelomocytes. olaEx1015 rescues egl-15(n484) suppression of cima-1 AIY presynaptic defects. Reference: Shao Z, et al. Cell. 2013 Jul 18;154(2):337-50.
DCR1779 cima-1(wy84) IV; egl-15(n484) wyIs45 X; olaEx1054. wyIs45 [ttx-3p::GFP::rab-3 + unc-122p::RFP] X. olaEx1054 [dpy-7p::egl-15(5A)(ecto) + unc-122p::GFP]. Maintain by picking animals with GFP expression in coelomocytes. olaEx1054 rescues egl-15(n484) suppression of cima-1 AIY presynaptic defects. Reference: Shao Z, et al. Cell. 2013 Jul 18;154(2):337-50.
DR1191 daf-12(m20) unc-27(e155) egl-15(n484) X. Dauer defective. Egl-60% form bags of worms. Unc-sluggish, poor backing. Resistant to both imipramine and serotonin. Slightly Dpy.
MP154 unc-8(e15) IV; egl-15(n484) sup-42(lb88) X. Egl. Unc slightly suppressed; the animals will usually back some. [unc-8(e15); egl-15(n484) animals are extremely Unc and will not back.]
MT1079 egl-15(n484) X. Egg laying defective. Makes bags of worms. Males mate.
MT3324 lon-2(e678) egl-15(n484) X.
MT3353 egl-15(n484) sma-5(n678) X. Small. Egl. Slow growing.
MT3433 egl-15(n1458) X. Egl. Maintain under normal conditions. Reference: DeVore DL, et al. Cell. 1995 Nov 17;83(4):611-20.
MT3443 egl-15(n484) sdc-1(n485) X.
MT3456 egl-15(n1477) X. Temperature sensitive Egl.
MT3458 egl-15(n1457) X. Egl. Maintain under normal conditions. Reference: DeVore DL, et al. Cell. 1995 Nov 17;83(4):611-20.
MT3460 +/szT1 I; dpy-6(e14) egl-15(n1454)/szT1 [lon-2(e678)] X. WT strain which segregates WT, Dpy L1 lethals, Lon males and dead eggs. Class II egl-15 mutation.
MT3790 unc-115(e2225) egl-15(n484) X. n484: Egl, displaced muscles. e2225: Unc-lethargic and kinker.
MT3870 clr-1(e1745) II; egl-15(n1477) X. Egl. Temperature sensitive Scrawny-cannot be maintained at 25C. Class III egl-15 mutation.
MT4039 clr-1(e1745) II; egl-15(n1783) X. non-Egl. non-Scrawny. Class IV egl-15 mutation.
MT4732 clr-1(n1992) II; egl-15(n1477) X. Non-Scr, non-Clr. Egl.
MT5554 clr-1(e1745) II; egl-15(n2202) X. Soc. Maintain under normal conditions. Reference: DeVore DL, Development. 2003 Aug;130(16):3757-66.
MT5562 clr-1(e1745) II; egl-15(n2210) X. Soc. Maintain under normal conditions. Reference: DeVore DL, Development. 2003 Aug;130(16):3757-66.
NH2038 clr-1(e2530) II; egl-15(n1477) X. Non-Scr, non-Clr. Egl.
NH2044 egl-15(ay1) X. Egl. Maintain under normal conditions. Reference: Chen EB, et al. Dev Biol. 1997 Feb 1;182(1):88-100.
NH2267 let-60(n1046) IV; egl-15(n1454) X. Unc and scrawny, but viable. Egl. Class II egl-15 mutation. Lethality suppressed by let-60.
NH2447 ayIs2 IV. ayIs2 [egl-15p::GFP + dpy-20(+)] IV. GFP expression in vm1 sex muscles and other miscellaneous cells.
NH2693 +/szT1 [lon-2(e678)] I; egl-15(n1456)/szT1 X. Heterozygotes are WT and segregate WT, Lon Males, early L1 larval arrested animals (n1456 homozygotes) and dead eggs. n1456 is an early nonsense mutation in the extracellular domain of EGL-15/FGFR (Q268 STOP).
NH3027 ncl-1(e1865) III; egl-15(n1456) X; ayEx86. ayEx86 [col-19::GFP + egl-15(+) (NH#112) + ncl-1(+)(c33c3)]. Maintain by picking non-Egl. Referene: Lo TW, et al. Dev Biol. 2008 Jun 15;318(2):268-75.
OH3455 oyIs14 V; egl-15(n1456) X; otEx1254. oyIs14 [sra-6::GFP + lin-15(+)]. otEx1254 [pTB70=egl-15p::egl-15(5B) genomic hybrid + ceh-22p::GFP + pBS]. otEx1254 rescues the lethal phenotype of egl-15(n1456).
OH3467 oyIs14 V; egl-15(n1456) X; otEx1267. oyIs14 [sra-6::GFP + lin-15(+)]. otEx1267 [pTB71=egl-15p::egl-15(5B) genomic hybrid + ceh-22p::GFP + pBS]. otEx1267 rescues the lethal phenotype of egl-15(n1456).
OH3478 oyIs14 V; egl-15(n484) X; otEx1270. oyIs14 [sra-6::GFP + lin-15(+)]. otEx1270 [dpy-7p::egl-15(5A)cDNA + ceh-22p::GFP + pBS]. Maintain by picking worms with GFP expression in their pharynx.
PB2 him-5(e1490) V; vab-3(bx23) egl-15(n484) X. Type A Egl. Males abnormal-fused rays. See also WBPaper00002235.
PJ1078 clr-1(e1745) II; ccIs55 V; egl-15(n1783) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Non-Egl. Non-Scrawny. Class IV egl-15 mutation. Supresses the temperature-sensitive Clr phenotype.
VC1782 +/szT1 [lon-2(e678)] I; egl-15(ok2314)/szT1 X. F58A3.2. Apparent homozygous lethal deletion chromosome balanced by lon-2-marked translocation. Heterozygotes are WT, and segregate WT, Lon-2 males, arrested szT1 aneuploids, and ok2314 homozygotes (arrest stage/phenotype undetermined). Pick WT and check for correct segregation of progeny to maintain. External left primer: CTTGCGCGTGTTTAGTTCTG. External right primer: CAACGCTTCTAAAGCCATCC. Internal left primer: TTTTTGCAGGGTCTTTGGTC. Internal right primer: ACAAGATGGCGTTGTGTCAA. Internal WT amplicon: 2895 bp. Deletion size: 1208 bp. Deletion left flank: GTAGTGCTCGGTCCGGCGGATACGAATTCA. Deletion right flank: TTTTAATTGCGTTTCAGGAAATCGCAGTTG. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807