Gene Information: pdk-1

Namepdk-1 View on WormBase
Species C. elegans
SequenceH42K12.1
Genetic positionX:-18.39 +/- 0.051 cM
Genomic positionX: 1321344..1327986

Strains carrying this gene

Strain Genotype Description
CY399 sqt-1(sc13) age-1(mg109) II; pdk-1(mg261) X. Sqt phenotype. The pdk-1(mg261) allele is a dominant suppressor of age-1(mg109) daf-c phenotype. mg261 is an activating missense mutation Ala447Val.
GR1318 pdk-1(mg142) X. No visible phenotype. Dominant suppressor of daf-c phenotype of age-1. Ala303Val substitution.
GR1322 pdk-1(sa680) X; mgEx470. mgEx470 [pdk-1(+) + ttx-3::GFP]. Pick GFP+ to maintain. 9.2-kb PCR product of genomic DNA from the pdk-1(+) genomic region containing 2.7 kb of 5' upstream regulatory sequence, 6.1 kb of coding sequencing containing introns and exons, and 0.4 kb of pdk-1 3' UTR. Reference: Paradis S, et al. Genes Dev. 1999 Jun 1;13(11):1438-52.
JT10066 unc-1(e719) pdk-1(sa680) X. Unc. Daf-c at 25C. Egl, Clumpy, Lon, low brood size. Dauers do not recover when moved to 15C in the presence of food. Daf-c, Lon, Clumpy and fertility defects can be rescued maternally. Maintain at 15C.
JT709 pdk-1(sa709) X. Daf-c at 27C. Weakly Egl and Clumpy. Maintain at 15C.
JT9609 pdk-1(sa680) X. Daf-c at 25C. Egl, Clumpy, Lon, low brood size. Dauers do not recover when moved to 15C in the presence of food. Daf-c, Lon, Clumpy and fertility defects can be rescued maternally. Maintain at 15C.
PJ1134 ccIs55 V; pdk-1(mg142) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. No visible phenotype (may be smallish??). Dominant suppressor of daf-c phenotype of age-1.
PJ1146 daf-2(m41) III; ccIs55 V; pdk-1(mg142) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Gain of function allele of pdk-1.
PJ1162 ccIs55 V; unc-1(e719) pdk-1(sa680) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Unc - recessive kinker. Daf-c at 25C. Egl, Clumpy, Lon, low brood size. Dauers do not recover when moved to 15C in the presence of food. Daf-c, Lon, Clumpy, and fertility defects can be rescued maternally.