Gene Information: sod-3

Namesod-3 View on WormBase
Species C. elegans
SequenceC08A9.1
Genetic positionX:24.07 +/- 0.002 cM
Genomic positionX: 17092753..17094306

Strains carrying this gene

Strain Genotype Description
CF1553 muIs84. muIs84 [(pAD76) sod-3p::GFP + rol-6(su1006)]. Green expression in head, tail and around vulva. Many animals roll weakly or not at all, but still express GFP. Grows at all temperatures.
CF1580 daf-2(e1370) III; muIs84. muIs84 [(pAD76) sod-3p::GFP + rol-6(su1006)]. Green expression in head, tail and around vulva. Daf-C at 25C. Grows well at 20C.
CF1588 daf-16(mu86) I; daf-2(e1370) III; muIs84. muIs84 [(pAD76) sod-3p::GFP + rol-6(su1006)]. Dim green expression in head, tail and around vulva. Daf-d. Can grow at 20C.
CF1660 daf-16(mu86) I; daf-2(e1370) III; muIs84; muEx211. muIs84 [(pAD76) sod-3p::GFP + rol-6(su1006)]. muEx211 [ges-1p::daf-16::GFP + rol-6(su1006)]. Pick Rollers to maintain. Partial rescue of lifespan phenotype. Some animals show variable daf-16 expression in the intestine. Grows okay at 15C. [NOTE: muEx211 is quite unstable. Be sure to pick Rollers to avoid losing the array.]
CF1874 daf-16(mu86) I; muIs84. muIs84 [(pAD76) sod-3p::GFP + rol-6(su1006)]. Green expression in head, tail and around vulva.
GA186 sod-3(tm760) X. Superficially wild-type.
GA480 sod-2(gk257) I; sod-3(tm760) X. Slow growing. Reduced brood size. Hypersensitive to oxidative stress.
KN259 huIs33. huIs33 [sod-3::GFP + rol-6(su1006)]. Pick Rollers to maintain.
KN478 daf-16(mu86) I; huIs33. huIs33 [sod-3::GFP + rol-6(su1006)]. Pick Rollers to maintain.
MQ1766 sod-2(ok1030) I; sod-5 (tm1146) sod-1(tm783) II; sod-4(gk101) III; sod-3(tm760) X. Normal lifespan. Increased sensitivity to oxidative stress, osmotic stress, cold stress, and heat stress. Slow development, slow physiological rates (thrashing, defecation), and reduced fertility. van Raamsdonk J & Hekimi S. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5785-90.
TM127 daf-2(e1370) III; sod-3(sj134) X. High frequency of dauer formation under hyperoxia (90% oxygen) at 20C. Reference: Honda Y, Tanaka M, Honda S, (2008) Exp Gerontol 43:520-9.
TM151 sod-2(sj173) I; daf-2(e1370) III; sod-3(sj134) X. Hypersensitive to Paraquat. Growth arrest under hyperoxia (90% oxygen) at any larval stage. Reference: Honda Y, Tanaka M, Honda S, (2008) Exp Gerontol 43:520-9.
VC433 sod-3(gk235) X. C08A9.1. Superficially wild type. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807