Gene Information: mab-5

Namemab-5 View on WormBase
Species C. elegans
SequenceC08C3.3
Genetic positionIII:-0.59 +/- 0.003 cM
Genomic positionIII: 7776835..7783454

Strains carrying this gene

Strain Genotype Description
CB3256 mab-5(e1751) III. Semidominant Unc(mild). Intragenic revertants common.
CB3299 mab-5(e1239) III; him-5(e1490) dpy-21(e428) V. Hermaphrodites are Dpy and segregate males. Males are non-Dpy and Mab. Both sexes show lineage alterations.
CB3531 mab-5(e1239) III; him-5(e1490) V. Males abnormal.
CB4711 mab-5(e1239) egl-5(n945) III. n945: HSN-. Egl. Coiler.
CF196 muIs3 V. muIs3 [mab-5::lacZ + rol-6(su1006)] V. Rollers.
CF237 muIs2 unc-31(e169) IV. muIs2 [mab-5::lacZ + unc-31(+)]. non-Unc.
CF301 mab-5(e2088) III; unc-31(e169) IV; him-5(e1490) V; muIs9 X. muIs9 [hs-mab-5 + C14G10]. Heat-shock inducible mab-5. C14G10 contains a WT copy of unc-31. muIs9 integrated by gamma irradiation.
CF311 mab-5(e1239) egl-5(n945) III; him-5(e1490) V.
CF65 mab-5(e2088) III; lin-22(n372) IV; him-5(e1490) V. mab-5 mutation affects ectodermal and mesodermal lineages. lin-22 and him-5 mutations affect neuroblast formation from the epidermal precursor cell V5.
KK204 sma-4(e729) mab-5(e1239) unc-36(e251) III. Small and Unc.
KX110 ced-9(n1653) mab-5(mu14) III; bcIs39 V. bcIs39 [lim-7p::ced-1::GFP and lin-15(+)] V.  Temperature sensitive induction of germ cell apoptosis at 25 C. Large number of germ cells are decorated by CED-1::GFP within 48 h. Activates CED-3-mediated cleavage of IFG-1, visualized by western blot (Contreras, V., et al, 2011).
MT3970 mab-5(mu14) ced-9(n1653) III. Temperature sensitive. About 50% HSN missing. Mab confirmed by Hillel Schwartz 12/5/00. Rec'd new stock from Horvitz lab 12/2000. [NOTE: The genotype of this strain was incorrectly described as carrying mab-5(mu114); however, the actual allele is mab-5(mu14).]
MT7238 sma-3(e491) mab-5(e1239) egl-5(n945)/lin-39(n1760) mab-5(e1239) egl-5(n945) III.
MT7255 lin-39(n1760) mab-5(e1239) egl-5(n945) III. Small brood size. Semi-sterile. n945: HSN-. Egl. Coiler.
MT7419 lin-39(n1760) mab-5(e1239)/sma-3(e491) mab-5(e1239) III.
VC1477 mab-5(gk670) III. C08C3.3. External left primer: TACTGGTTGCGAGATTGCTG. External right primer: TTCATGCTCCTCCCAATTTC. Internal left primer: GTTCCTGTCTTCAAGGCGAC. Internal right primer: ATTCACACGTTGTTCGCATC. Internal WT amplicon: 2178 bp. Deletion size: 920 bp. Deletion left flank: AAAAACCTGTGAGAAATTTACAACAATTGA. Deletion right flank: TGCTCATTTGCCGACGGATTGAGTTGAGGG. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807