Gene Information: clr-1

Nameclr-1 View on WormBase
Species C. elegans
SequenceF56D1.4
Genetic positionII:-1.31 +/- 0.026 cM
Genomic positionII: 5466358..5473816

Strains carrying this gene

Strain Genotype Description
CB3241 clr-1(e1745) II. Temperature sensitive lethal: inviable at 25C, grows at 20C and 15C. Somewhat sickly. Small brood sizes. At 25C homozygotes have a starved translucent appearance, facilitating Nomarski visualization of neuron processes.
MT3870 clr-1(e1745) II; egl-15(n1477) X. Egl. Temperature sensitive Scrawny-cannot be maintained at 25C. Class III egl-15 mutation.
MT3989 clr-1(e1745) bli-2(e768) II. Adult Blistered, especially in the head. Starved translucent appearance at 20c; inviable at 25C.
MT4030 clr-1(e1745) II; soc-2(n1774) IV. clr-1 suppressed.
MT4035 clr-1(e1745) II; sem-5(n1779) X. About 11% of the animals should be Vulvaless. n1779 suppresses clr-1.
MT4039 clr-1(e1745) II; egl-15(n1783) X. non-Egl. non-Scrawny. Class IV egl-15 mutation.
MT4045 clr-1(e1745) II; soc-1(n1789) V. clr-1 suppressed.
MT4106 clr-1(e1745) dpy-10(e128) II. Maintain at 15C.
MT4732 clr-1(n1992) II; egl-15(n1477) X. Non-Scr, non-Clr. Egl.
MT5104 lin-31(n301) clr-1(e1745) dpy-10(e128) II. Dpy. Muv. Starved translucent appearance at 20c; inviable at 25C.
MT5449 clr-1(e1745) II; let-60(n2021) IV. Non-Lethal allele of let-60. Clear. Suppresses n765. Maintain at 15C.
MT5554 clr-1(e1745) II; egl-15(n2202) X. Soc. Maintain under normal conditions. Reference: DeVore DL, Development. 2003 Aug;130(16):3757-66.
MT5562 clr-1(e1745) II; egl-15(n2210) X. Soc. Maintain under normal conditions. Reference: DeVore DL, Development. 2003 Aug;130(16):3757-66.
NH2020 clr-1(e1745) II; sem-5(n1619) X. Vulvaless. About 91% of the animals die as L1 or early L2. n1619 suppresses clr-1.
NH2038 clr-1(e2530) II; egl-15(n1477) X. Non-Scr, non-Clr. Egl.
PJ1070 clr-1(e1745) II; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Clear. Grows very poorly at 25C.
PJ1078 clr-1(e1745) II; ccIs55 V; egl-15(n1783) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Non-Egl. Non-Scrawny. Class IV egl-15 mutation. Supresses the temperature-sensitive Clr phenotype.
PJ1110 clr-1(e1745) II; lin-45(sy96) IV; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. sy96 appears to suppress the Clr phenotype of e1745. Lots of Bags and larval lethals.
PJ1114 clr-1(e1745) II; mpk-1(n2521) III; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. clr-1 is termperature-sensitive.
PJ1124 mek-2(ku114) I; clr-1(e1745) II; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Egl. Bags at high frequency. Semi-Clr.
PJ1126 clr-1(e1745) II; ccIs55 V; sem-5(n1779) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. clr-1 is temperature-sensitive. n1779 suppresses clr-1.
PJ1153 clr-1(e1745) II; let-756(s2613) unc-32(e189) III; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Homozygous viable and fertile, but slow-growing, transparent, and small (but not scrawny). Coiler Unc. clr-1 is temperature-sensitive.
PJ1154 clr-1(e1745) II; ccIs55 V; egl-17(n1377) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Egl - moderate to severe bloating. 30% make bags of worms. Clr.
PJ1158 clr-1(e1745) II; let-756(s2613) unc-32(e189) III; ccIs55 V; egl-17(n1377) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Egl: moderate to severe bloating. Clr-1 is ts. Homozygous viable and fertile, but slow-growing, transparent, and small (but not scrawny). Coiler Unc.
PJ1283 clr-1(e1745) II; unc-51(e369) ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Clr fairly well suppressed by unc-51.
PJ1290 clr-1(e1745) II; unc-43(e408) IV; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Very slow movement. Clr phenotyope is difficult to score.
TL24 zdIs5 I; clr-1(cy14) II; slt-1(eh15) X. zdIs5 [mec-4::GFP + lin-15(+)]. cy14 was isolated in a screen for suppressors of the AVM axon ventral guidance defect of slt-1 null mutant. cy14 is a G-to-A transition in the splice acceptor of intron 5 of clr-1 that leads to the use of a cryptic splice acceptor and consequently to an 18 bp deletion in exon 6.
VC4303 clr-1(gk5386[loxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + loxP])/+ II. Apparent homozygous lethal or sterile deletion as unbalanced heterozygote. Deletion of 6585 bp with Calarco/Colaiacovo selection cassette conferring myo-2::GFP and G418 resistance inserted at break. Pick viable fertile GFP+ animals to maintain. Left flanking sequence: TCGGTGAGTTTTTTTAAAAGAAGGACTAAC. Right flanking sequence: ATGTTTACCCGTTTTGAGCAGTATTCTTTC. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.