| CB3031 |
unc-17(e245) IV; snb-1(e1563) V. |
Dominant suppressor of Unc. Movement almost WT. |
| NM1081 |
snb-1(js124)/dpy-11(e224) unc-68(r1158) V. |
Heterozygotes are WT and segregate WT, DpyUncs and L1 lethals. js124 homozygotes arrest as L1 larvae that are very uncoordinated and tend to adopt a coiled position. js124 molecular lesion is an amber mutation at codon 50. |
| NM306 |
jsIs1. |
jsIs1 [(pSB120) snb-1::GFP + rol-6(su1006)]. Rollers. GFP expressed in the nerve ring, ventral cord and dorsal cord. Received new stock 3/10/2008 from Mike Nonet. Faint signal using a dissecting microscope. Obvious signal using a compound microscope (40X oil). |
| NM440 |
unc-104(e1265) II; jsIs1. |
jsIs1 [(pSB120) snb-1::GFP + rol-6(su1006)]. Roller. Unc. GFP expressed in the nerve ring, ventral cord, dorsal cord. |
| NM467 |
snb-1(md247) V. |
Aldicarb resistant. Lethargic Unc - jerky especially in backward movement. Low pumping rate. Molecular lesion for md247 is a 20 bp duplication yielding a frameshift mid-way through the transmembrane domain. |
| NM534 |
snb-1(js17) V. |
Aldicarb resistant. Unc. L62F mutant (C to T in first base of codon). |
| NM833 |
snb-1(js44) V. |
Aldicarb resistant. Unc. A65G mutant (C to T in second base of codon). |
| RM3645 |
unc-17(e245) IV; snb-1(e1563) V. |
Almost full suppression of all unc-17 mutant phenotypes; animals are superficially wild type in appearance, development, and behavior, and males mate well. For additional information, see descriptions of the RM908 unc-17(e245) IV and the RM3659 snb-1(e1563) V single mutant strains. Reference: Sandoval GM, et al. Nat Neurosci. 2006 May;9(5):599-601. |
| RM3659 |
snb-1(e1563) V. |
e1563 homozygotes are superficially wild-type in appearance, development, and behavior. e1563 is a strong, dominant suppressor of UNC-17 G347R mutations (including e245, e359, p300). Molecular details: e1563 corresponds to an I97D (att>>gat) missense mutation in the SNB-1 transmembrane domain. Reference: Sandoval GM, et al. Nat Neurosci. 2006 May;9(5):599-601. |