Gene Information: cat-4

Namecat-4 View on WormBase
Species C. elegans
SequenceF32G8.6
Genetic positionV:2.60 +/- 0.002 cM
Genomic positionV: 10564880..10566464

Strains carrying this gene

Strain Genotype Description
CB1141 cat-4(e1141) V. Catecholamine abnormal. Recessive. M-MATING++ 1-10%WT.
CF250 cat-4(e1141) him-5(e1490) V. Catecholamine abnormal. Throws males.
LC141 him-8(e1489) IV; cat-4(e3015) V. Reduction in serotonin and dopamine, most apparent in young larva; bleach hypersensitivity and cuticle fragility in adult, but less than null mutants. Derived by outcrossing CB7107 six times to N2. Reference: Loer CM, et al. Genetics. 2015 May;200(1):237-53.
LC35 cat-4(ok342) V. T21C9.2, F32G8.6. Serotonin-deficient by anti-serotonin staining. Bleach hypersensitive. Likely also dopamine-deficient (but not tested). Slightly sickly. External left primer: TTTCTTTTCTTGTTGCGCCT. External right primer: TCGAAAAAGTCTGCTTCGGT. Internal left primer: CGTCTTCCGTTTCTTTTTCG. Internal right primer: TCTTGGAATGTGGGATGTGA. Internal WT amplicon: 2497 bp. Deletion size: 2238 bp. Deletion left flank: CGACTAGATTGATTTCCTTCTGTCCCTTCA. Deletion right flank: CTTGACGGAACAACGCCTCGATCTGATCTC. This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. URL: http://www.celeganskoconsortium.omrf.org.
LC81 cat-4(tm773) V. Serotonin and dopamine-deficient, bleach hypersensitive, general chemical hypersensitivity, fragile cuticle. 652 bp deletion removes entire first exon. Derived by outcrossing FX773 five times to N2.
MT8943 bas-1(ad446) III; cat-4(e1141) V. Cat. Serotonin minus.