Gene Information: lin-1

Namelin-1 View on WormBase
Species C. elegans
SequenceC37F5.1
Genetic positionIV:-8.39 +/- 0.146 cM
Genomic positionIV: 2275861..2300286

Strains carrying this gene

Strain Genotype Description
CB1026 lin-1(e1026) IV. Multi-vulva (Muv).
CB1275 lin-1(e1275) IV. Temperature sensitive. Lineage abnormal. Multi-vulva. M-MATING+POOR <1%WT.
CF32 lin-1(e1026) IV; him-5(e1490) V. Very slow growth.
DA664 egl-4(ad450) lin-1(e1777) IV. Muv. ad450 worms, when undisturbed, fall asleep. While asleep they do not move or pump. Disturbing them wakes them up, and while awake they act fairly normal. ad450 previously called eat-7.
FX17650 lin-1(tm5929)/tmIn1 IV. Homozygous lethal or sterile deletion allele balanced by Unc-marked translocation. Break points: In(egl-4 unc-17) IV. Covered region (Mb) 1.8 (1.8..3.6) Unc. Reference: Iwata S, et al. Sci Rep. 2016 Sep 21;6:33840.
FX19170 lin-1(tm5929)/tmIn2 IV. Homozygous lethal or sterile deletion allele balanced by Unc-marked translocation. Break points: In(ced-2 unc-17) IV. Covered region (Mb) 2 (1.6..3.6) Unc. Reference: Iwata S, et al. Sci Rep. 2016 Sep 21;6:33840.
KG115 lin-1(e1275) unc-33(e204)/ric-8(ok98) IV. ok98/+ animals are slightly Egl-d and have a small vulval bump. ok98 homozygotes are straight and paralyzed and slow growing. About 2/3 eventually reach adulthood and are paralyzed and sterile (they produce few if any oocytes). Segregates Unc Muv(ts).
MT1001 lin-1(e1777) IV. Multivulva. Amber. No male mating. Not Null.
MT1006 lin-1(n431) IV. Strong Muv.
MT10869 ced-10(n3417)/lin-1(e1275) dpy-13(e184) IV. Heterozygotes are semi-Dpy. Throws DpyLins and DTC-defective progeny.
MT176 lin-1(n176) IV. Strong Muv.
MT2125 lin-1(n1047) IV. Strong Muv.
MT303 lin-1(n303) IV. Muv.
MT3516 lin-1(e1275) cha-1(p1152) IV. Temperature sensitive Multi-vulva. Slow growing. Unc-coils, jerky going backward. Small.
MT383 lin-1(n383) IV. Strong Muv.
MT4578 lin-1(e1275) dpy-13(e184) IV; unc-9(e101) X. Temperature sensitive Muv. Semi-dominant Dpy. Unc-moves backward better than forward; slight kinker in forward movement; larvae more severly Unc.
MT6996 dpy-9(e12) ced-2(e1752) lin-1(e1275) IV. Dpy. Temperature sensitive Muv. Abnormal cell death.
MT7195 lin-1(n757) IV. Strong Muv.
MT7567 lin-1(sy254) IV. Strong Muv. Null.
MT7949 lin-1(n1761) IV. n1761 cuases a partially penetrant "rod-like" larval lethal phenotype (70% at 20C) and a partially penetrant vulvaless phenotype (30% at 20C). It is a splice site defect predicted to eliminate 62 amino acids at the C-terminus.
MT8022 lin-1(n304) IV. Strong Muv. Null.
MT8256 lin-1(n304) IV/nT1 [unc-?(n754) let-?] (IV;V). Heterozygotes are Unc and segregate Unc, Muvs and dead eggs.
MT8384 lin-1(sy254) IV/nT1 [unc-?(n754) let-?] (IV;V). Heterozygotes are Unc and segregate Unc, Muv and dead eggs.
RW12212 lin-1(st12212[lin-1::TY1::EGFP::3xFLAG]) IV. lin-1(st12212[lin-1::TY1::EGFP::3xFLAG]) IV.
WU125 lin-1(n1790) IV. n1790 causes a partially penetrant "rod-like" larval lethal phenotype (17% at 20C) and a partially penetrant vulvaless defect (50% at 20C). A Smg mutation enhances these phenotypes. The n1790 mutation is a nonsense change at codon 352.
WU156 lin-1(n2515) dpy-13(e184) IV. n2515 suppresses the let-60(gf) Muv phenotype. Isolation of lin-1 causes no significant vulval defect; it is a missense mutation that changes Proline 384 to Leucine. dpy-13 is a linked marker.