Gene Information: unc-75

Nameunc-75 View on WormBase
Species C. elegans
SequenceC17D12.2
Genetic positionI:9.28 +/- 0.021 cM
Genomic positionI: 11592246..11601712

Strains carrying this gene

Strain Genotype Description
CB950 unc-75(e950) I. Unc-weak coiler, especially in reverse; moves forward well; sluggish; short.
DA502 unc-75(e950) unc-101(m1) I. Unc. Eat.
DR210 dpy-5(e61) daf-16(m26) unc-75(e950) I. Dauer defective. Dpy. Unc. Leaky.
DR211 daf-16(m26) unc-75(e950) I. Dauer defective. Unc.
FX30208 tmC27 [unc-75(tmIs1239)] I. Break points: In(ile-1 Y18D10A.2 In(dnj-27 dkf-1)) I. Covered region (Mb) 4 (9.6..13.6) Balancer marked with myo-2p::Venus. Unc. Reference: Dejima K, et al. Cell Rep. 2018 Jan 2;22(1):232-241.
FX30258 tmC27 [unc-75(tm9711)] I. Break points: In(ile-1 Y18D10A.2 In(dnj-27 dkf-1)) I. Covered region (Mb) 4 (9.6..13.6) Unc. Reference: Dejima K, et al. Cell Rep. 2018 Jan 2;22(1):232-241.
JJ1079 hmr-1(zu389)/lin-11(n566) unc-75(e950) I. Heterozygotes are WT and segregate WT, Hmr inviable embyros and Egl Unc. Hmr: Hammerhead - defective hypodermal enclosure, especially in anterior regions; approximately 2% of zu389 embryos enclose normally and are Hmp [Humpback: defective body elongation, abnormal bulges on dorsal side]. See also WBPaper00005031. Received new stock from Allison Lynch in the Hardin lab 3/2009.
JK1542 ces-1(n703) qDf7/dpy-5(e61) srf-2(yj262) unc-75(e950) I. Heterozygotes are Srf and grow slowly. Hets segregate Srf, DpyUncSrf and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. CGC rec'd new stock 10/99.
KR2839 hDf15 unc-75(e950)/hIn1 [unc-54(h1040)] I. Wild-type phenotype. Segregates WT, Unc-54 (hIn1[unc-54] homozygotes), dead eggs (hDf15 homozygotes). Pick WT and check for correct segregation of progeny to maintain. See WBG 14: 29. This deletion was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose. CGC received new stock 9/3/97.
ML653 vab-10(mc44)/unc-75(e950) unc-101(m1) I. Heterozygotes are WT and segregate WT, Uncs and dead eggs and larvae with severe body morphology defects that do not develop beyond the L2 stage. A few very rare mc44 larvae reach adulthood but they become sterile. mc 44 is a deletion affecting the downstream transcription unit of vab-10 named vab-10b. Fails to complement the vab-10 null reference allele vab-10(h1356), but complements the vab-10a alleles vab-10a(e698) and vab-10a(ju281).
ML691 vab-10(ok817)/unc-75(e950) unc-101(m1) I. Heterozygotes are WT and segregate WT, Uncs, and severely Lumpy arrested L1s (ok817). m1 can easily get lost through recombination.
MT3618 unc-75(e950) ced-1(n1506) unc-59(e261) I.
MT3637 lin-11(n566) unc-75(e950) I.
MT6550 lam-3(n2561)/dpy-5(e61) unc-75(e950) I. Heterozygotes are WT. Segregate Dpy Uncs. Segregate L1 lethal: starved, uncoordinated, defective pharyngeal basement membrane.
RM2005 unc-75(md1344) I. Small, coily Unc; aldicarb resistant. 780-bp deletion: TTCGGTTCGTGTTTTTTATTGATATTTTTT /-----/ACAACATCCATTCGTCACAAGCTGCTATCA. Reference: Loria PM, et al., Curr Biol. 2003 Aug 5;13(15):1317-23.
SU112 hmr-1(zu389)/lin-11(n566) unc-75(e950) I; jcIs1 IV. jcIs1 [ajm-1::GFP + unc-29(+) + rol-6(su1006)] IV. Heterozygotes are Rollers and segregate Rollers, Hmr inviable embyros and Egl Unc. ajm-1 was formerly known as jam-1 (Junction Associated Protein) and "the gene encoding the antigen recognized by the monoclonal antibody MH27." jcIs1 consists of pJS191, C45D3 and pRF4. Reference: Koppen M, et al. Nat Cell Biol. 2001 Nov;3(11):983-91.