Gene Information: unc-108

Nameunc-108 View on WormBase
Species C. elegans
Genetic positionI:-2.01 +/- 0.057 cM
Genomic positionI: 3822883..3826514

Strains carrying this gene

Strain Genotype Description
CB713 unc-108(e713) I. Unc. M-MATING++ 1-10%WT. Previously called unc-67.
KP5832 unc-108(nu415) I. Reference: Chun DK, et al. Mol Biol Cell. 2012; 19, 2682-95.
MT1093 unc-108(n501) I. Dominant Slow.
MT1656 unc-108(n777) I. Dominant Unc.
VC829 unc-108(ok1246) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). F53F10.4. Homozygous lethal deletion chromosome balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP ok1246 homozygotes (early- to mid-larval arrest). Homozygous hT2[bli-4 let-? qIs48] inviable. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype. Pick WT GFP and check for correct segregation of progeny to maintain. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807
ZH382 unc-108(n3263) I. Recessive Unc. Recessive apoptotic cell removal defect. Recessive phagosome maturation defect (inefficient and prolonged phagosome maturation process in embryos). Reference: Mangahas PM, Yu X, and Zhou Z. J Cell Biol. 2008 Jan 28;180(2):357-73.