Gene Information: sma-3

Namesma-3 View on WormBase
Species C. elegans
SequenceR13F6.9
Genetic positionIII:-0.92 +/- 0.001 cM
Genomic positionIII: 6860974..6863968

Strains carrying this gene

Strain Genotype Description
CB491 sma-3(e491) III. Small. Recessive. Males abnormal-abnormal spicules. M-MATING-NO SUCCESS.
CS119 sma-3(wk30) III; him-5(e1490) V; qcEx24. qcEx24 [GFP::sma-3 + rol-6(su1006)]. Rollers. Pick rollers to maintain. Array rescues body size phenotype. Reference: Wang J, Tokarz R, Savage-Dunn C. Development. 2002 Nov;129(21):4989-98.
CS210 sma-3(wk30) III; him-5(e1490) V; qcEx52. qcEx52 [myo-2p::GFP::sma-3 + rol-6(su1006)]. Sma. Rollers. Pick rollers to maintain. Reference: Wang J, Tokarz R, Savage-Dunn C. Development. 2002 Nov;129(21):4989-98.
CS211 sma-3(wk30) III; him-5(e1490) V; qcEx53. qcEx53 [vha-6p::GFP::sma-3 + rol-6(su1006)]. Sma. Rollers. Pick rollers to maintain. Reference: Wang J, Tokarz R, Savage-Dunn C. Development. 2002 Nov;129(21):4989-98.
CS619 sma-3(wk30) III; qcIs59. qcIs59 [vha-6p::GFP::sma-3 + rol-6(su1006)]. Small Rollers. GFP::SMA-3 fusion protein is expressed in the intestine. Derivative of a strain described in Wang et al., 2002, Development 129:4989-4998.
CS628 sma-3(wk30) III; qcIs55. qcIs55 [vha-7p::GFP::sma-3 + rol-6(su1006)]. Rollers. Transgene drives tissue-specific expression of SMA-3 in the hypodermis; rescues the small body size phenotype. Reference: Clark JF, et al. 3: GENES, GENOMES, GENETICS January 1, 2018 vol. 8 no. 1 343-351.
EH250 sma-3(e491) unc-32(e189) III.
JK1774 eef-1A.1(q145)/sma-3(e491) unc-36(e251) III. Heterozygotes are WT and segregate WT, SmaUnc and Steriles. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be used for any commercial purpose or for work on human subjects. eft-3(q145) previously called glp-3(q145).
LT153 sma-3(wk28) III. Small body size.
LT85 sma-3(wk20) III. Small body size.
LW614 arIs37 I; sma-3(jj3) cup-5(ar465) III. arIs37 [myo-3p::ssGFP + dpy-20(+)] I. Small body size and 6 coelomocytes. myo-3p::ssGFP is a secreted GFP that is taken up by coelomocytes.
MT3026 lin-8(n111) II; sma-3(e491) lin-37(n758) unc-36(e251) III. Small. Unc. Muv.
MT3040 lin-8(n111) II; sma-3(e491) unc-36(e251) III. SmaUnc. Not Muv.
MT3061 lin-8(n111) II; sma-3(e491) lin-13(n387) unc-36(e251)/sma-3(e491) lin-37(n758) III. Heterozygotes are Sma. At 25C, hets segregate Sma, SmaMuv (lin-8; sma-3 lin-37), and SmaUncMuvSte (lin-8; sma-3 lin-13 unc-36). At 15C, hets segregate Sma, SmaMuv (lin-8; sma-3 lin-37) and SmaUnc which give sterile F2 (lin-8; sma-3 lin-13 unc-36). n387 is a ts maternal effect mutation.
MT4837 sma-3(e491) lin-39(n1490) III. Small. Vulvaless (temperature sensitive-91% Vul at 15C and 100% Vul at 20C and 25C). n1490 is also temperature sensitive Unc.
MT7238 sma-3(e491) mab-5(e1239) egl-5(n945)/lin-39(n1760) mab-5(e1239) egl-5(n945) III.
MT7419 lin-39(n1760) mab-5(e1239)/sma-3(e491) mab-5(e1239) III.
NH2296 ceh-20(ay42) unc-36(e251)/sma-3(e491) unc-36(e251) III. Heterozygotes are Unc and segregate Unc, SmaUnc and UncVul. ay42 is a strong Vul and is recessive. ay42 has slow growth.
NH2552 ceh-20(ay38) unc-36(e251)/sma-3(e491) unc-36(e251) III. Heterozygotes are Unc and segregate Unc, SmaUnc and larval lethals. Putative null allele.
PJ1225 sma-3(wk28) III; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Small body size, slow growth. Strong lacZ staining in body wall.
ST20 ncIs2 II; mup-4(nc20)/sma-3(e491) unc-32(e189) III. ncIs2 [pH20::GFP + pBlueScript]. Heterozygotes are WT and segregate WT, SmaUnc, and animals with muscle attachment defects and ventral cord displacement and detachment which arrest in larval development or as embryos. Not well balanced. Neurons visualized with NcIs2.