Gene Information: unc-43

Nameunc-43 View on WormBase
Species C. elegans
Genetic positionIV:4.58 +/- 0.001 cM
Genomic positionIV: 10324254..10350217

Strains carrying this gene

Strain Genotype Description
CB408 unc-43(e408) IV. Marginally Unc-no sin wave. Lethargic. Recessive. M-MATING-NO SUCCESS.
CG118 unc-43(sy574) IV; him-5(e1490) V. Males constitutively protract their spicules in the absence of mating cues.
CG460 unc-43(sy574) IV; him-5(e1490) V; rgEx161. rgEx161[lev-11p::UNC-43g + gtl-1p::CFP]. rgEx161 rescues unc-43(sy574)-induced spicule protraction.
JJ1129 elt-1(zu180) unc-43(e408)/unc-24(e138) dpy-20(e1282) IV. Heterozygotes are WT and segregate WT, DpyUncs and dead eggs.
JT200 unc-43(sa200) IV. Defecation motor program executed twice each cycle period. Hyperactive loopy movement. Previously called dec-8(sa200).
MT1092 unc-43(n498) IV. Gain of function allele. Small, almost paralyized. Egl. Semi-dominant. daf-C at 27C.
MT2598 unc-43(n498n1179) IV.
MT2605 unc-43(n498n1186) IV.
NM1378 unc-43(js125) V. Unc. Maintain under normal conditions. Reference: Hawasli A, et al. Genetics. 2004 Oct;168(2):831-43.
PJ1182 unc-43(n498) IV; ccIs55 V; njEx38. ccIs55 [unc-54::lacZ + sup-7(st5)] V. njEx38 [unc-54p::daf-2(+) + goa-1p::GFP + rol-6(su1006)]. Rollers. Pick Rollers to maintain. unc-43 gain-of-function. Progressive paralysis.
PJ1270 unc-43(n408) IV; ccIs55 V; csEx52. ccIs55 [unc-54::lacZ + sup-7(st5)] V. csEx52 [hsp::lin-45AA + sur-5::GFP]. Unc slow. Array is unstable, pick GFP+ to maintain.
PJ1290 clr-1(e1745) II; unc-43(e408) IV; ccIs55 V. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Very slow movement. Clr phenotyope is difficult to score.
PJ1305 unc-43(n498j038) IV; ccIs55; njEx38. ccIs55 [unc-54::lacZ + sup-7(st5)] V. njEx38 [unc-54p::daf-2(+) + goa-1p::GFP + rol-6(su1006)]. Rollers. Pick Rollers to maintain. unc-43 gain-of-function suppressed; not markedly small. Egl-d. Lethal @ 25C; short L1's do not survive. No GFP expression.
VC1052 unc-43(gk452) IV. K11E8.1c. Superficially wild type. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807
XM1007 fog-3(q443) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); unc-43(n498) IV. Heterozygotes are Unc with pharyngeal GFP signal. Homozygous hT2[bli-4 let-? qIs48] are inviable. Homozygous unc-43(n498); fog-3(q443) animals are females.