Gene Information: lon-1

Namelon-1 View on WormBase
Species C. elegans
Genetic positionIII:-1.63 +/- 0.012 cM
Genomic positionIII: 5474476..5478005

Strains carrying this gene

Strain Genotype Description
ATD3 lon-1(e185) par-3(e2074) unc-119(ed3) III; zuIs45 V; sDp3(III;f) zuIs45 [nmy-2p::nmy-2::GFP + unc-119(+)] V. Pick wild-type to maintain. Worms carrying the sDp3 duplication are wild-type; animals that have lost the duplication are Lon Par (maternal effect lethal). Cross of JJ1473 and KK237. Unknown if unc-119(ed3) is still present or homozygous in background. Reference: Small LE & Dawes AT. Mol Biol Cell. 2017 Aug 1;28(16):2220-2231.
CB185 lon-1(e185) III. Long. Abnormal bursae. Epistatic to Small. Recessive. M-MATING-NO SUCCESS.
CB1918 lon-1(e185) unc-32(e189) III. Long. Unc. Linked closely.
CB2206 lon-1(e185) daf-4(e1364) unc-32(e189) III. Temperature sensitive dauer constitutive. Long. Unc. Linked closely.
CB2305 lon-1(e185) sup-5(e1464) III. Lon, slow-growing. Very poor growth at less than 20C.
DR1096 lon-1(e185) unc-36(e251) III. Very long, thin, and slow moving.
EG1000 dpy-5(e61) I; rol-6(e187) II; lon-1(e1820) III. Dpy suppresses Rol and Lon. Strain appears to be only Dpy. Useful for mapping, especially Unc mutations. Separately, dpy-5 causes extreme dumpiness, rol-6 causes worms to roll over and lie in a "C" shape, and lon-1 worms are about 125% WT length.
EU918 lon-1(e185) par-3(it71)/qC1 [dpy-19(e1259) glp-1(q339)] III; spn-4(or191) V. Temperature sensitive spn-1. Maintain at 15C. Lethal at 25C. Heterozygotes are WT and segregate WT, Lon which give only dead eggs at all temperatures, and Sterile Dpys(ts).
JJ1600 par-3(it71) lon-1(e185) III; him-8(e1489) IV; zuIs20. zuIs20 [par-3p::par-3::ZF1::GFP + unc-119(+)]. Lon. Him. GFP-tagged PAR-3 that is degraded in early embryonic somatic cells. Rescues the Par phenotype of par-3(it71). Delayed endodermal cell gastrulation. Reference: Nance J, Munro EM, Priess JR. Development. 2003 Nov;130(22):5339-50.
JT5516 saDf1/lon-1(e185) III. Heterozygotes are WT and segregate WT, Lon and dead eggs. Hets are slow growing and sick.
KK237 lon-1(e185) par-3(e2074) III; sDp3 (III;f). WT sDp3-bearing animals segregate WT and lon-1 par-3 homozygotes that lay eggs that don't hatch. par-3 exhibits mildly ts penetrance in homozygotes. Strict maternal effect. Received new stock 3/01.
KK241 lon-1(e185) par-3(it62) III; sDp3 (III;f). Animals with the Duplication are WT. Animals which have lost the Duplication are Lon and throw dead eggs.
KK571 lon-1(e185) par-3(it71)/qC1 [dpy-19(e1259) glp-1(q339)] III. Heterozygotes are WT and segregate WT, Dpy Steriles, and Lon which give only dead eggs.
MT1803 lin-8(n111) II; lon-1(e185) lin-37(n758) III. Long. Muv.
MT2330 dpy-17(e164) lon-1(e1820) III.
MT2422 lon-1(n1130) III. Long. Can split in two.
MT405 dpy-1(e1) lon-1(e185) III.
MT4979 lon-1(e185) ced-6(n1813) unc-32(e189) ced-7(n1892) III. ced-6(n1813): dead cells persist, maternal rescue of embryonic. Unc. Long.
MT4981 lon-1(e185) ced-6(n1813) III; ced-10(n1993) IV. ced-10(n1993): cell corpses unengulfed. Long.
RL67 lon-1(e185) let-711(it150) unc-32(e189)/qC1 [dpy-19(e1259) glp-1(q339)] III. Heterozygotes are WT and segregate WT, Dpy Steriles, and Lon Uncs which are temperature sensitive maternal effect lethals. Embryos from homozygyous it150 hermaphrodites have spindle orientation defects at second and third cleave at 25C.