Gene Information: vab-1

Namevab-1 View on WormBase
Species C. elegans
SequenceM03A1.1
Genetic positionII:-3.85 +/- 0.013 cM
Genomic positionII: 4572000..4590970

Strains carrying this gene

Strain Genotype Description
CB2 vab-1(e2) II. Notched head. Penetrance <70%.
CZ1774 vab-1(e856) ptp-3(op147)/mIn1 [mIs14 dpy-10(e128)] II. mIs14 [myo-2::GFP + pes-10::GFP]. Homozygous lethal double mutant balanced by GFP- and dpy-10-marked inversion. Pick wild-type GFP+ to maintain. Heterozygotes are wild-type with pharyngeal GFP signal, and segregate wild-type GFP+, Dpy bright GFP+ (mIn1 homozygotes), and non-GFP homozygous vab-1 ptp-1 double mutants. vab-1 ptp-1 double mutants (non-GFP) are embryonic lethal. Reference: Harrington RJ, et al. Development. 2002 May;129(9):2141-53.
CZ337 vab-1(dx31) II. Strong Vab-1 phenotype. About 50% embryonic lethality and about 30% larval lethality. Genetic null.
CZ375 vab-1(e856) II.
CZ414 vab-1(e699) II. Intermediate Vab-1 phenotype. About 9% embryonic lethality and about 20% larval lethality. CB699 outcrossed 2X to N2 to make CZ414.
CZ429 vab-1(ju8) II.
CZ5686 vab-1(e2027) ptp-3(mu256)/mIn1 [mIs14 dpy-10(e128)] II. mIs14 [myo-2::GFP + pes-10::GFP]. Homozygous lethal double mutant balanced by GFP- and dpy-10-marked inversion. Pick wild-type GFP+ to maintain. Heterozygotes are wild-type with pharyngeal GFP signal, and segregate wild-type GFP+, Dpy bright GFP+ (mIn1 homozygotes), and non-GFP homozygous vab-1 ptp-1 double mutants. vab-1 ptp-1 double mutants (non-GFP) are embryonic lethal. Reference: Harrington RJ, et al. Development. 2002 May;129(9):2141-53.
CZ7112 lin-31(n301) vab-1(e2027) II. Muv.
CZ793 vab-1(e2027) II; lin-15B&lin-15A(n765) X; juIs24. juIs24 [vab-1::GFP + lin-15(+)]. GFP very faint. Overtly WT.
CZ910 vab-1(e2027) II. vab-1 null phenotype. e2027 is a 74 bp deletion allele.
DG1612 vab-1(dx31)/mIn1 [dpy-10(e128) mIs14] II; fog-2(q71) V. Maintain by mating GFP+ females with GFP+ males.
DG1650 vab-1(dx31)/mIn1 [dpy-10(e128) mIs14] II; fog-2(q71) V; ceh-18(mg57) X. Maintain by mating GFP+ females with GFP+ males.
IC136 zdIs5 I; vab-1(dx31) II. zdIs5 [mec-4::GFP + lin-15(+)].Animals contain GFP expressed in the touch neurons and have a notched head phenotype.
IC361 vab-1(e2)/mIn1 [dpy-10(e128) mIs14] II; sax-3(ky123) X. Heterozygotes are WT and GFP+. mIn1 homozygotes are Dpy and GFP+. vab-1; sax-3 homozygotes are synthetic lethal.
OH4130 bwIs2 vab-1(dx31) II; wrk-1(ok695) X. bwIs2 [flp-1::GFP + rol-6(su1006)]. Segregates >90% Rollers and 100% GFP+. Expresses GFP in the AVK neurons. Insertion site not mapped.
OH4132 vab-1(dx31) II; rhIs4 III; wrk-1(ok695) X. rhIs4 [glr-1p::GFP + dpy-20(+)] III.
OH4133 bwIs2 II; vab-1(dx31) II. bwIs2 [flp-1::GFP + rol-6(su1006)]. Segregates >90% Rollers and 100% GFP+. Expresses GFP in the AVK neurons. Insertion site not mapped.
OH4139 vab-1(dx31) II; oyIs14 V. oyIs14 [sra-6::GFP + lin-15(+)].
OH4140 vab-1(dx31) II; oyIs14 V; wrk-1(ok695) X. oyIs14 [sra-6::GFP + lin-15(+)].
OH4143 vab-1(dx31) II; zdIs13 IV. zdIs13 [tph-1p::GFP] IV.
OH4144 vab-1(dx31) II; zdIs13 IV; wrk-1(ok695) X. zdIs13 [tph-1p::GFP] IV.
VC1255 vab-1(ok1699) II. M03A1.1. Superficially wild type. External left primer: CACGACGATAAGCGGTTTTT. External right primer: TAAGGCTCGGGTACCGTATG. Internal left primer: GTGTACCTCACCCCCTCTCA. Internal right primer: TCTGATTACGCAGTCATCGC. Internal WT amplicon: 3217 bp. Deletion size: 1016 bp. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807
XM1002 vab-1(dx31) III; itr-1(sy290) unc-24(e138) IV. vab-1 null and itr-1 gain of function. Viable. Unc.