Gene Information: dat-1

Namedat-1 View on WormBase
Species C. elegans
SequenceT23G5.5
Genetic positionIII:0.36 +/- 0.010 cM
Genomic positionIII: 9242975..9246802

Strains carrying this gene

Strain Genotype Description
BZ555 egIs1. egIs1 [dat-1p::GFP] Bright GFP observable in dopamine neuronal soma and processes. For some reason this strain is resistant to neurotoxic effects of 6-OHDA compared to an independent strain BY200 (Nass et al., 2002). Or maybe BY200 is more sensitive to 6-OHDA due to its co-injection marker gene rol-6?
RM2702 dat-1(ok157) III. Cosmid coordinates (with respect to T23G5): 24967-26802 (or 24965-26800, or 24966-26801, or 24968-26803, or 24969-26804 - note that each deletion endpoint lies within a TATA sequence so there is some ambiguity in the precise endpoints). Flanking sequences: CTATTCGGATATCTTGCCAATGCTA//TAGGAATTATTTTTGCGCTCTCAGG. Deletion size: 1836 bp.
TG2401 dat-1(ok157) III; vtIs1 V; tsp-17(gt1681) X. vtIs1 [dat-1p::GFP + rol-6(su1006)] V. Many animals roll weakly or not at all, but still express GFP. Reference: Masoudi N, et al. PLoS Genet. 2014 Dec 4;10(12):e1004767.