Gene Information: unc-23

Nameunc-23 View on WormBase
Species C. elegans
Genetic positionV:1.86 +/- 0.014 cM
Genomic positionV: 8936359..8939684

Strains carrying this gene

Strain Genotype Description
BW1118 mel-25(ct60) unc-42(e270)/unc-23(e25) vab-8(e1017) V; lon-2(e678) X. Maintain by picking Lon non-Unc. Throws Lon non-Unc, Lon Unc Vab (bent head, tails very thin), and Lon Unc Mel (kinker, temperature-sterile).
BW219 nDf31/unc-23(e25) sma-1(e30) V. Heterozygotes are WT and segregate SmaUnc and Lethals. Lethal in L1. Maintain by picking WT.
CB25 unc-23(e25) V. Unc.
CB324 unc-23(e324) V. Unc. Head muscles degenerative. Recessive. M-MATING+POOR <1%WT.
CB611 unc-23(e611) V. Head abnormal. Variable expression. M-MATING+++ 10-30%WT.
DM1602 hsp-1(ra807) IV; unc-23(e25) V. Superficially wild-type. Temperature-sensistive. Maintain at 15C. hsp-1(ra807) is a missense allele that replaces the conserved Ala379 residue to a Val residue in the ATPase domain of the HSP-1 protein and fully suppresses the bent-head phenotype of unc-23(e25). Animals are sterile or arrest development as larvae at when grown at 20-25C. Reference: Rahmani P, Rogalski T, Moerman DG. (2015) Worm. In press.
DM5130 unc-23(e25) V; raEx20. raEx20 [unc-23::GFP + rol-6(su1006) + pPD95.75(GFP)]. Rollers. Pick Rollers to maintain. raEx20 encodes a functional GFP::tagged UNC-23 protein. Reference: Rahmani P, Rogalski T, Moerman DG. (2015) Worm. In press.
RB1301 unc-23(ok1408) V. H14N18.1 Homozygous. Outer Left Sequence: tgaaagcaaacgagacatcg. Outer Right Sequence: accaccacctgatctcttgc. Inner Left Sequence: ttttctgtctcacggagcct. Inner Right Sequence: ccagaaaagggacaaccgta. Inner Primer PCR Length: 2756. Estimated Deletion Size: about 1100 bp. Attribution: This strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807
RW3570 unc-112(st562)/dpy-11(e224) unc-23(e25) V. Heterozygotes are WT and segregate WT, DpyUnc and Pats. Maintain by picking WT and checking for correction segregation of progeny.
TH37 dpy-11(e224) unc-23(e25) V. Dpy. Unc.