Gene Information: unc-2

Nameunc-2 View on WormBase
Species C. elegans
Genetic positionX:-13.79 +/- 0.063 cM
Genomic positionX: 2710920..2763526

Strains carrying this gene

Strain Genotype Description
BC13255 dpy-5(e907) I; sEx13255. sEx13255 [rCesT02C5.5b::GFP + pCeh361]. Maintain by picking WT. WT animals are GFP+. Strain construction supported by Genome British Columbia and Genome Canada. Please acknowledge McKay et al, Cold Spring Harbor Symposia on Quantitative Biology 68: 159-169 2004 (WBPaper00006525).
CB3912 eT2 (X;I)/unc-2(e55) X. Heterozygotes are WT and segregate WT, Unc and dead embryos. eT2 homozygotes are embryonic lethals.
CB55 unc-2(e55) X.
DA1031 egl-19(n582) IV; unc-2(e55) X. Unc. Egl, Lon, Slow and Floppy.
DA1034 egl-19(n2368) IV; unc-2(e55) X. Unc. Semidominant Egl-c, Sma.
DA1035 egl-19(ad695) IV; unc-2(e55) X. Unc. Semi-dominant Eat (TB relaxation defective).
DM612 unc-2(ra612) X.
HH123 unc-2(e55) unc-7(hs10) X. unc-124 is a cold sensitive kinker Unc.
JU42 Oscheius tipulae unc-2(mf29). Sluggish Unc. Recessive autosomal. Parental strain Oscheius tipulae CEW1. AKA Oscheius sp. 1.
MLC524 unc-2(luc27) X. luc27 is a 300 bp deletion in the unc-2 3'UTR. Reference: Drexel T, et al. Genes Dev. 2016 Sep 15;30(18):2042-2047.
MU1080 unc-2(e55) fax-1(gm83) X. unc-2(e55) is very inactive. gm83 is a Unc (forward kinker). Double shows both phenotypes.
NL735 unc-2(pk95::Tc1) X.
OK257 peb-1(cu9)/dpy-3(e27) unc-2(e55) X. Heterozygotes are WT and segregate WT, DpyUncs, and peb-1(cu9) homozygotes which arrest as larvae with a stuffed pharynx, abnormal hindgut and g1 gland cell morphology, and molting defects.
PJ1045 ccIs55 V; unc-2(e55) X. ccIs55 [unc-54::lacZ + sup-7(st5)] V. Slow moving Kinkers. Slow growing.
PS1032 syDf1/unc-2(e55) lon-2(e678) X. Heterozygotes are Lon non-Unc. Df/Df is embryonic lethal. Maintain by picking single Lon non-Unc and check for dead embryos-->Lon non-Unc recombinants that have lost the Df arise frequently. Does not survive long periods of starvation-->survivors tend to be Lon non-Uncs without the Df. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
SP521 dpy-3(e27) unc-2(e55) X. Dpy. Unc.
TS337 unc-2(e55) lin-15B&lin-15A(n765) X; vaIs33. vaIs33 [unc-2::GFP + lin-15(+)]. Superficially Wild-type.
TY2025 yDp14 (X;I); unc-2(e55) X. non-Unc hermaphrodite strain. yDp14/+; unc-2 males are 60% inviable. yDp14/yDp14; unc-2 males are dead.
TY2071 him-8(e1489) IV; dpy-3(e27) unc-2(e55) X; yDp16 (X;f). non-Unc, somewhat Dpy hermaphrodites. Gives DpyUncs when yDp16 is lost.
VC854 unc-2(gk366) X. T02C5.5a. Unc. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807