Gene Information: unc-46

Nameunc-46 View on WormBase
Species C. elegans
SequenceC04F5.3
Genetic positionV:-2.52 +/- 0.029 cM
Genomic positionV: 5097075..5099025

Strains carrying this gene

Strain Genotype Description
BC3471 dpy-18(e364)/eT1 III; sDf41 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT, dead eggs, and no Unc-36 or DpyUnc-46. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3472 dpy-18(e364)/eT1 III; unc-46(e177) sDf44/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3473 dpy-18(e364)/eT1 III; sDf45 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3474 dpy-18(e364)/eT1 III; unc-46(e177) sDf47/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3476 dpy-18(e364)/eT1 III; sDf49 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3539 dpy-18(e364)/eT1 III; sDf50 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3540 dpy-18(e364)/eT1 III; sDf51 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT, dead eggs, and no Unc-36 or DpyUnc-46. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3541 dpy-18(e364)/eT1 III; sDf52 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3551 dpy-18(e364)/eT1 III; let-426(s1527) unc-46(e177)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC3555 dpy-18(e364)/eT1 III; unc-46(e177) let-467(s1521)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval (hatches). Maintain by picking WT.
BC3557 dpy-18(e364)/eT1 III; unc-46(e177) let-340(s1508)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC3559 dpy-18(e364)/eT1 III; let-415(s1525) unc-46(e177)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC3564 dpy-18(e364)/eT1 III; let-327(s1496) unc-46(e177)/eT1 V. Hets are Slow, have Morphological Abnormalities, and are lethal at 25C. Segregate hets, Unc-36 dead eggs, and DpyUncLet.
BC3590 dpy-18(e364)/eT1 III; unc-46(e177) let-433(s950)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUnc sterile adults and dead eggs. Maintain by picking WT.
BC3592 dpy-18(e364)/eT1 III; unc-46(e177) let-434(s1904)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUnc sterile adults and dead eggs. Maintain by picking WT.
BC3655 dpy-18(e364)/eT1 III; unc-46(e177) let-468(s1533)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC3670 dpy-18(e364)/eT1 III; lag-2(s1486) unc-46(e177)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval, mid-larval at 15C. Maintain by picking WT. Previously called let-461(s1486).
BC3674 dpy-18(e364)/eT1 III; unc-46(e177) let-470(s1581)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC3684 dpy-18(e364)/eT1 III; unc-46(e177) let-472(s1605)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC3698 dpy-18(e364)/eT1 III; unc-46(e177) let-411(s1595)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC3700 dpy-18(e364)/eT1 III; unc-46(e177) pst-1(s1594)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal embryo to early larval. Maintain by picking WT.
BC3702 dpy-18(e364)/eT1 III; unc-46(e177) let-402(s1526)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC3712 dpy-18(e364)/eT1 III; unc-46(e177) let-474(s1577)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC3713 dpy-18(e364)/eT1 III; unc-46(e177) let-473(s1602)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT. [This strain is acting strangely: it is throwing bent heads. 12/95]
BC3716 dpy-18(e364)/eT1 III; unc-46(e177) let-475(s1606)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet (Sterile adult) and dead eggs. Maintain by picking WT.
BC3718 dpy-18(e364)/eT1 III; unc-46(e177) let-407(s1631)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval (hatches). Maintain by picking WT.
BC3727 dpy-18(e364)/eT1 III; sDf56 unc-46(e177)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, and dead eggs. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3728 dpy-18(e364)/eT1 III; unc-46(e177) let-480(s1607)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet (Sterile adult) and dead eggs. Maintain by picking WT.
BC3729 dpy-18(e364)/eT1 III; let-478(s1620) let-?(s2169) unc-46(e177)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC3731 dpy-18(e364)/eT1 III; unc-46(e177) let-479(s1576)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet (Sterile adult-> Lays unfertilized eggs) and dead eggs. Maintain by picking WT.
BC3732 dpy-18(e364)/eT1 III; unc-46(e177) let-418(s1617)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet (Sterile adult; Vulva protrudes; partial rescue at 15C) and dead eggs. Maintain by picking WT.
BC3733 dpy-18(e364)/eT1 III; let-481(s1636) unc-46(e177)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, DpyUncLet and dead eggs. Lethal early larval (hatches). Maintain by picking WT.
BC3953 dpy-18(e364)/eT1 III; sDf70 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT, no Unc36, DpyUncLet and dead eggs. Lethal early larval. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3954 dpy-18(e364)/eT1 III; unc-46(e177) sDf71/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. Embryonic lethal. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3955 dpy-18(e364)/eT1 III; sDf72 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. Embryonic lethal. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3956 dpy-18(e364)/eT1 III; sDf73 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT, dead eggs, no Unc-36, and DpyUncLet. Lethal early larva. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3957 dpy-18(e364)/eT1 III; sDf74 unc-46(e177)/eT1 [let-500(s2165)] V. WT strain which segregates WT and dead eggs. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC3958 dpy-18(e364)/eT1 III; sDf75 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. Embryonic lethal. Maintain by picking WT. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC4011 srl-1(s2500) II; dpy-18(e364) III; unc-46(e177) rol-3(s1040) V. srl-1 is a recessive suppressor of the s1040 temperature sensitive lethal phenotype. srl-1 has no effect on the Roller phenotype of s1040. (At 20C, s1040 homozygotes arrest development at mid-larval stage. At 15C, s1040 homozygotes are viable weak left-handed rollers.) Maintain at 20C to select for retention of suppressor. Animals at 20C will be DpyUncRol.
BC4425 dpy-18(e364)/eT1 III; sDf48 unc-46(e177)/eT1 [let-500(s2165)] V. Heterozygotes are WT and segregate WT and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BW1747 dpy-18(e364)/eT1 III; unc-46(e177) let-427(s1057)/eT1 V. Heterozygotes are WT and segregate WT, Unc-36, Sterile DpyUncs and dead eggs. Maintain by picking WT.
CB177 unc-46(e177) V. Unc. Recessive. M-MATING++ 1-10%WT.
CGC20 dpy-18(e364)/eT1 III; unc-46(e177)/eT1[umnIs9] V. umnIs9 [myo-2p::GFP + NeoR, III:9421936 (intergenic)] V. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, Unc-36 GFP+ (eT1), dead eggs, and DpyUncs. Maintain by picking wild-type GFP+. Derived by insertion of myo-2p::GFP transgene into eT1 balancer in parental strain BC2200 using CRISPR/Cas9.
CGC23 dpy-18(e364)/eT1 [umnIs12] III; unc-46(e177)/eT1 V. umnIs12 [myo-2p::GFP + NeoR, V: 1005689 (intergenic)] III. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, Unc-36 GFP+ (eT1), dead eggs, and DpyUncs. Maintain by picking wild-type GFP+. Derived by insertion of myo-2p::GFP transgene into eT1 balancer in parental strain BC2200 using CRISPR/Cas9.
CGC60 dpy-18(e364)/eT1 III; unc-46(e177)/eT1[umnIs46] V. umnIs46 [myo-2p::mKate2 + NeoR, III:9421936 (intergenic)] V. Heterozygotes are wild-type mKate+, and segregate wild-type mKate2+, Unc-36 mKate+ (eT1), dead eggs, and DpyUncs. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into eT1 balancer in parental strain BC2200 using CRISPR/Cas9.
CGC69 dpy-18(e364)/eT1 [umnIs55] III; unc-46(e177)/eT1 V. umnIs55 [myo-2p::mKate2 + NeoR, V:1005689 (intergenic)] III. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, Unc-36 mKate+(eT1), dead eggs, and DpyUncs. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into eT1 balancer in parental strain BC2200 using CRISPR/Cas9.
DG832 emb-30(tn475)/eT1 III; unc-46(e177) mdf-1(gk2)/eT1 V. Heterozygotes are WT and segregate WT, Unc-46 Steriles, and Unc-36 (eT1 homozygotes). Maintain by picking WT.
DG844 emb-30(tn377) III; unc-46(e177) mdf-1(gk2) V. emb-30(tn377ts) conditionally suppresses mdf-1(gk2). Maintain at 15C.
GS401 let-418(ar113)/unc-46(e177) dpy-11(e224) V. Heterozygotes are WT and segregate WT, Steriles with an Everted Vul and DpyUncs. ar113 pka evl-11(ar113). Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS402 let-418(ar114)/unc-46(e177) dpy-11(e224) V. Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. ar114 pka evl-11(ar114). Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.