Gene Information: unc-22

Nameunc-22 View on WormBase
Species C. elegans
SequenceZK617.1
Genetic positionIV:5.46 +/- 0.005 cM
Genomic positionIV: 11972697..12011007

Strains carrying this gene

Strain Genotype Description
BA836 spe-26(it112) unc-22(e66) IV. Temperature-sensitive. Fertile at 15C. Partially fertile at 20C. Sterile at 25C. Twitcher. Spermatogenesis arrests at the spermatocyte stage.
BA839 spe-26(it118) unc-22(e66) IV. Temperature-sensitive. Fertile at 15C. Partially fertile at 20C. Sterile at 25C. Twitcher. Spermatogenesis arrests at the spermatocyte stage.
BA966 spe-27(it132) unc-22(e66) IV. Temperature sensitive spe-27 allele. Hermaphrodites sterile at 25C; hermaphrodites produce 30-40 progeny/hermaphrodite at 16C. Males cannot mate due to the unc-22 mutation. Maintain at 15C.
BA970 spe-6(hc163) III; spe-27(it132) unc-22(e66) IV. Twitcher Unc. spe-6(hc163) is a recessive suppressor of spe-27(it132). spe-6(hc163) also suppresses spe-8, spe-12, spe-29 and other spe-27 alleles. Causes precocious spermatid activation. Fertile between 15-25C.
BC1291 let-93(s734) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC1548 unc-22(s7) let-67(s214)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul and Twitcher Steriles. The sterility can be rescued by male sperm.
BC177 unc-22(s17) IV. Twitcher. Both heterozygotes and homozygotes twitch in 1% nicotine.
BC18 unc-22(s13) IV. Twitcher Unc. Heterozygotes twitch in 1% Nicotine. Recessive.
BC1907 let-68(s1081) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul and LetUncTwitcher. Lethal ??. Maintain by picking WT.
BC1912 let-652(s1086) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Egl, dead eggs and UncLets. Lethal early larval. Maintain by picking WT.
BC200 unc-22(s12) IV. Twitcher Unc. Recessive. Heterozygotes twitch in 1% Nicotine.
BC2001 let-98(s1117) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet and dead eggs. Lethal late larval. Maintain by picking WT.
BC2003 let-96(s1112) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, Lethal Twitchers and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC2008 unc-22(s7) unc-31(e169) let-315(s1101)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC2010 let-60(s1124) unc-22(s7) unc-31(e169) IV/nT1 (IV;V). Heterozygotes are WT and segregate WT, Vul and UncLethals. Strong allele of let-60. Unc Twitchers arrest as rod-like early larvae; rare escapers die as Vul adults.
BC2013 unc-22(s7) let-97(s1121) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, UncLet (Twitcher), Vul, and dead eggs. Lethal early larval. Maintain by picking WT.
BC2020 let-70(s1132) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet (twitchers) and dead eggs. Lethal early larval. Maintain by picking WT. See also WBPaper00002501.
BC2021 let-289(s1133) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2024 let-291(s1139) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2029 let-60(s1155) unc-22(s7) unc-31(e169) IV/nT1 (IV;V). Heterozygotes are WT and segregate WT, Vul and Twitcher UncLethals. s1155 is viable; 14% Vul.
BC2034 let-292(s1146) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2035 unc-22(s7) unc-31(e169) let-317(s1153)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Egl, UncLet and dead eggs. Lethal at embryo-early larval. Maintain by picking WT.
BC2036 let-100(s1160) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet and dead eggs. Lethal early larval. Maintain by picking WT.
BC2037 let-293(s1166) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are short and somewhat Egl. Offspring are short. Segregate Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Not outcrossed!
BC2047 let-290(s1140) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2049 let-658(s1149) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, UncLet, Egl and dead eggs. Maintain by picking WT.
BC2053 let-307(s1171) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Egl, Lethal Twitchers and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC2060 let-311(s1195) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet and dead eggs. Lethal late larval. Maintain by picking WT.
BC2061 let-69(s1111) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Egl, Lethal Twitchers and dead eggs. Lethal early larval. Maintain by picking WT.
BC2063 unc-22(s7) let-309(s1115) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet and dead eggs. Lethal late larval. Maintain by picking WT.
BC2067 let-659(s1152) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, UncLet, Egl and dead eggs. Maintain by picking WT.
BC2069 let-651(s1165) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, Lethals and dead eggs. Maintain by picking WT.
BC2070 let-294(s1103) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2079 unc-22(s7) unc-31(e169) let-301(s1134)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet, and dead eggs. Lethal early larval. Maintain by picking WT.
BC2088 let-295(s1175) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2094 unc-22(s7) unc-31(e169) let-313(s1135)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, Sterile Unc, and dead eggs. Maintain by picking WT.
BC21 unc-22(s8) IV. Twitcher Unc. Recessive. Heterozygotes twitch in 1% Nicotine.
BC2105 let-308(s1705) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Egl, Lethal Twitchers and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC2107 unc-22(s7) unc-31(e169) let-314(s1206)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Egl, UncLet and dead eggs. Lethal at embryo-early larval. Maintain by picking WT.
BC2113 unc-22(s7) unc-31(e169) let-318(s1218)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, Sterile Uncs and dead eggs. Maintain by picking WT.
BC2120 unc-22(s7) unc-31(e169) let-321(s1228)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Egl, Sterile Unc, and dead eggs. Maintain by picking WT.
BC2124 unc-22(s7) unc-31(e169) let-322(s1238)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLets and dead eggs. Lethal mid-larval. Maintain by picking WT.
BC2126 let-657(s1254) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, UncLet, Vul and dead eggs. Maintain by picking twitchers (hets) in 1% nicotine.
BC2130 unc-22(s7) unc-31(e169) let-316(s1227)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul and TwitcherUncLet. Lethal ??. Maintain by picking WT.
BC2137 let-312(s1234) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, UncLet and dead eggs. Lethal late larval. Maintain by picking WT.
BC2144 unc-22(s7) unc-31(e169) let-320(s1248)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul and UncLet. Homozygous s1248 is a sterile adult. Maintain by picking WT.
BC2148 let-296(s1250) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vuls, early-mid larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC23 unc-22(s7) IV. Twitcher Unc. Recessive. Heterozygotes twitch in 1% Nicotine
BC2895 let-73(s685) unc-22(s7)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, Twitcher Steriles and dead eggs. Maintain by picking WT.
BC2897 let-72(s695) unc-22(s7)/nT1 IV; +/nT1 V. Heterozygotes are WT and segregate WT, Vul, dead eggs, and UncLets. Lethal mid-larval. Maintain by picking WT.