Gene Information: unc-15

Nameunc-15 View on WormBase
Species C. elegans
SequenceF07A5.7
Genetic positionI:2.06 +/- 0.000 cM
Genomic positionI: 7376604..7383197

Strains carrying this gene

Strain Genotype Description
BA811 sDf5/spe-4(hc78) unc-15(e73) I. Heterozygotes are WT and segregate WT heterozygotes, Sterile Unc spe-4 unc-15 homozygotes, and dead eggs (sDf5 homozygotes). Pick wild-type to maintain.
BC110 dpy-14(e188) unc-13(e51) let-85(s142)/unc-15(e73) I. Heterozygotes are WT and segregate WT, Unc and DpyUncLets. Lethal at L1. Maintain by picking WT.
BC112 dpy-14(e188) unc-13(e51) let-82(s85)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc, and DpyUncLet (DpyUnc Larvae are abnormal). Maintain by picking WT.
BC115 dpy-14(e188) unc-13(e51) let-81(s88)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncLets are abnormal larvae and die in early larval development. Pick WT to maintain.
BC123 dpy-14(e188) unc-13(e51) let-84(s91)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLet. The DpyUncs are abnormal larvae that die in late larval development. Pick WT to maintain.
BC124 dpy-14(e188) unc-13(e51) unc-37(s80)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLet. The DpyUncLet larvae are abnormal. Pick WT to maintain.
BC125 dpy-14(e188) unc-13(e51) let-79(s81)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethal. The DpyUncs are abnormal larvae that die in early larval development. Pick WT to maintain. Note 5/92: probably has lost dpy-14.
BC148 dpy-14(e188) let-75(s101) unc-13(e51)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae that die in early larval development (L1). Pick WT to maintain. Previously called myo-1(s101).
BC149 dpy-14(e188) unc-13(e51) let-83(s97)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUnc are abnormal larvae which die in early larval development. Pick WT to maintain.
BC157 dpy-14(e188) unc-13(e51) let-80(s96)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and Lethal DpyUncs. Lethal early larval. Pick WT to maintain.
BC160 dpy-14(e188) unc-13(e51) let-87(s106)/unc-15(e73) I. Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. Lethal early larval (L1). Maintain by picking WT.
BC162 dpy-14(e188) unc-13(e51) let-88(s132)/unc-15(e73) I. Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. The DpyUncs are abnormal larvae which die in early larval development. Pick WT to maintain.
BC165 dpy-14(e188) unc-13(e51) let-89(s133)/unc-15(e73) I. Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. Lethal early larval. Maintain by picking WT.
BC184 dpy-14(e188) unc-13(e51) bli-4(s90)/unc-15(e73) I. Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae which die in late larval development. Pick WT to maintain. s90 previously called let-77. See also WBPaper00003507. CGC received new stock 3/01.
BC199 sDf6/unc-15(e73) I. Heterozygotes are WT and segregate WT, Paralyzed Unc and Lethals (L1). Pick WT to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
BC215 dpy-14(e188) unc-13(e51) let-78(s82)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae which die in late larval development. Pick WT to maintain.
BC220 dpy-14(e188) unc-13(e51) let-90(s140)/unc-15(e73) I. Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. The DpyUncs are abnormal larvae. Pick WT to maintain.
BC244 dpy-14(e188) let-86(s141) unc-13(e51)/unc-15(e73) I. Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae which die in early larval development. Pick WT to maintain.
BC455 unc-15(e73) unc-13(e51) I. Paralysed Unc.
BC694 sDf5/unc-15(e73) I. Heterozygotes are WT and segregate more WT, Uncs and L1 lethals. Pick WT to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to David Baillie.
CB1214 unc-15(e1214) I. Limp paralyzed Unc. Larvae move slightly better. Egl. Disorganized muscle structure. Suppressed by sup-5 and sup-7.
CB1215 unc-15(e1215) I. Slow moving Unc. Paramyosin abnormal.
CB1402 unc-15(e1402) I. Temperature sensitive Unc-paralyzed. WT at 15C. leaky at 25C. Sterile at 25C.
CB2213 unc-15(e73) I; eDp22 V. Movement slow. Unc partially suppressed.
CB2220 unc-15(e73) I; eDp23 V. Movement almost WT. Unc suppressed.
CB2621 unc-15(e73) I; eDf1 eDp21/sma-1(e30) V. Heterozygotes are slow moving. Segregates paralysed small. eDf1 eDp21 homozygotes die in larval development.
CB73 unc-15(e73) I. Paralyzed Unc. Semi-dominant. M-MATING-NO SUCCESS.
DR115 unc-15(e73) unc-54(e675) I. Slow movement.
DR116 unc-15(e73) I; sma-1(e30) V. Small. Unc.
DR117 unc-15(e73) I; dpy-11(e224) V. Dpy. Unc. Very slow movement.
DR118 unc-15(e73) I; dpy-11(e224) eDp22 V.
DR297 unc-15(e1402) I; eDp23 V.
DR373 unc-15(e73) I; sus-1(m156) III; eDp23 V. Paralyzed Unc. sus-1 suppresses the ability of eDp23 to suppress unc-15. eDp23 = sup-3(e1407).
DR401 unc-15(e73) I; eDf1 eDp21/dpy-11(e224) V. Heterozygotes are slow moving. Hets segregate DpyUncs. Hets segregate larval lethals (eDf1 eDp21 homozygotes).
DR429 dpy-5(e61) unc-15(e73) I. Dpy. Unc. Semi-paralyzed.
DR605 unc-15(e73) I; sup-19(m210) V. Unc phenotype weakly suppressed. Very slow.
DR629 unc-15(e73) I; sus-1(m156) daf-2(e1370) III; eDp23 V. Temperature sensitive dauers. Paralyzed Unc. sus-1 suppresses the ability of eDp23 to suppress unc-15. eDp23 = sup-3(e1407).
DR632 unc-15(e73) I; sus-1(m156) III. Severly ill and paralyzed. Lays few eggs. More severe than unc-15 alone.
EM62 mab-17(e2167) unc-15(e73) I; him-5(e1490) V. Unc. Round bulging adult male tale. Very reduced fan. Mating efficiency is zero.
FX19181 unc-15(tm6329)/tmIn14 I. Homozygous lethal deletion allele balanced by Dpy-marked translocation. Break points: In(dpy-5 lin-10) I. Covered region (Mb) 2.7 (5.4..8.1) Dpy. [NOTE: the genotype originally listed for this strain in Table 2 of Dejima, et al. was incorrect.] Reference: Dejima K, et al. Cell Rep. 2018 Jan 2;22(1):232-241.
HE2000 unc-15(su2000) I. Paralyzed Unc. Super Slow. Body Muscle Abnormal. Sarcomeres faint.
HE228 unc-15(su228) I. Unc. Body Muscle Abnormal. Recessive.
JK1726 qDf16/dpy-5(e61) unc-15(e1402) I. Heterozygotes are WT and segregate WT, dead eggs and DpyUncs. Maintain by picking WT. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.