Gene Information: him-5

Namehim-5 View on WormBase
Species C. elegans
Genetic positionV:6.09 +/- 0.018 cM
Genomic positionV: 14090426..14092454

Strains carrying this gene

Strain Genotype Description
AD271 spe-38(eb44) I; him-5(e1490) V; asEx78. asEx78 [spe-38p::spe-38(cDNA)::spe-38 3'UTR + myo-3p::GFP]. Pick GFP+ to maintain. GFP+ worms are fertile; animals that have lost the array are sterile.
AD281 spe-45(as38) IV; him-5(e1490) V. Him. Temperature-sensitive sterile. Small brood size even at permissive temperatures; pick fertile animals and maintain at 15C. Worms lacking spe-45 function produce morphologically normal and motile sperm that cannot fuse with oocytes despite direct contact in the reproductive tract. spe-45 hermaphrodites and males are subfertile at 16C and sterile at 25C. Reference: Singaravelu G, et al. Current Biology 2015.
AV285 swm-1(me66) him-5(e1490) V. Sperm activation in virgin males. Poor sperm transfer.
AV322 swm-1(me87) him-5(e1490) V. Sperm activation in virgin males. Very poor sperm transfer.
BA1044 spe-27(it132) spe-29(it127) IV; him-5(e1490) V. Non-conditional hermaphrodite sterile. Males fertile. Self-progeny produced after mating.
BA1051 spe-12(hc76) I; spe-29(it127) IV; him-5(e1490) V. Self-sterile hermaphrodites; fertile males. Mated hermaphrodites produce self and outcross progeny. Self progeny are 33% males.
BA524 fer-1(hc1) I; him-5(e1490) V. Temperature sensitive. Maintain at 15C. Throws males.
BA547 fer-2(hc2) III; him-5(e1490) V. Fertile at 16c and 20C. Sterile at 25C-Produces some defective embryos and 0-5 progeny. Throws males.
BA562 fer-4(hc4) him-5(e1490) V. Temperature sensitive. Maintain at 15C. Produces about 30% males.
BA782 spe-10(hc104) him-5(e1490) V. Temperature sensitive, maintain at 16C. Segregates males. Average progeny at 16C is 7 +/- 5. Average progeny at 25C is 0.1 +/- .1.
BC4923 egl-38(sy294) IV; him-5(e1490) V.
BW1809 gpa-16(it143) I; him-5(e1490) V. Temperature-sensitve. Maintain at 15C. Slight Maternal Effect Lethal (Mel) at 15C, more pronounced at 20C. Highly penetrant Mel at 25C and a fraction of the survivors have reversed left-right organs.
BW1935 unc-119(ed3) III; ctIs43 him-5(e1490) V. ctIs43 [dbl-1p::GFP + dbl-1p::GFP::NLS + unc-119(+)].
CB1467 him-5(e1467) V. 20% XO self-progeny at 16C. Recessive. Temperature sensitive. M-MATING++++ >30%WT.
CB1490 ali-1(e1934) him-5(e1490) V. Faint or invisible alae in L1. Segregates males.
CB2338 mab-6(e1249) II; him-5(e1490) V. Segregates males. Males abnormal.
CB2810 tra-1(e1575)/+ III; unc-42(e270) him-5(e1490) dpy-21(e428) V. Pick Unc hermaphrodite to maintain (these will be tra-1/+; unc-42 him-5 dpy-21 XO animals). Segregates Unc hermaphrodites (tra-1/+ III), Unc males (+/+ III), and DpyUnc hermaphrodites (+/+ III). dpy-21 not expressed in XO. dpy-21(e428) V; XX animals are weak Dpy. dpy-21(e428) V; XO animals are non-Dpy.
CB3252 rnt-1(e1241) I; him-5(e1490) dpy-21(e428) V. Hermaphrodites are Dpy and Him. Males are non-Dpy and Mab. Males have abnormal bursa and defective rays. Both sexes show lateral hypodermis lineage defexts. M-MATING+POOR <1%WT.
CB3297 vab-9(e1744) II; him-5(e1490) V. Him. M-MATING+POOR <1%WT. Tail abnormalities->knob-like swelling in larvae and adults.
CB3298 him-5(e1490) dpy-21(e428) V; mab-7(e1599) X. Hermaphrodites are Dpy. Males are non-Dpy and have abnormal bursae in adult, with swollen rays. Males will mate, but with very low efficiency. [3/98: King Chow isolated a line from the CGC stock that was throwing 100% Mabs. Sent the strain back to the CGC to replace the old stock.]
CB3299 mab-5(e1239) III; him-5(e1490) dpy-21(e428) V. Hermaphrodites are Dpy and segregate males. Males are non-Dpy and Mab. Both sexes show lineage alterations.
CB3353 mab-9(e1245) II; him-5(e1490) dpy-21(e428) V. Hermaphrodites are Dpy and segregates males. Males are non-Dpy and have severe tail abnormalities; frequently lethal to adult males.
CB3518 mab-10(e1248) II; him-5(e1490) V. Hermaphrodtes segregate impotent males. Males show very slight swelling of bursa.
CB3531 mab-5(e1239) III; him-5(e1490) V. Males abnormal.
CB3855 plg-1(e2001) III; him-5(e1490) V. Hermaphrodites and males superficially WT. Males lay down a gelatinous plug over the vulva of mated hermaphrodites. Plug formation controlled only by male genotype. Both plg-1 and plg-1/+ males make plugs.
CB3924 pal-1(e2091) III; him-5(e1490) V. Males are missing most of the rays and additional alae extend into the tail.
CB4043 smg-2(e2008) I; him-5(e1490) V. e2008 recessively suppresses the phenotypes of mutations in unc-54(r293), lin-29(n546), tra-2 and dpy-5. Abnormal male tail. smg-2 homozygotes have slightly abnormal movement.
CB4088 him-5(e1490) V. From CB1490, which is a double mutant of him-5 with ali-1. CB4088 has been outcrossed to remove ali-1.
CB4104 mab-12(e2166) IV; him-5(e1490) V. Males have abnormal swollen bursa. Hermaphrodites have abnormal swollen vulva.
CB4111 mab-24(e2169) I; him-5(e1490) V. Anterior displacement of rays and fan. Ray identities are not altered. Slightly Unc (coiler).
CB4219 pal-2(e2260) IV; him-5(e1490) V. WT hermaphrodites. Mails have ectopic lateral alae in tail region. Segregates males.
CB4354 smg-3(ma117) IV; him-5(e1490) V. Hermaphrodites have an abnormal protrusive vulva. Segregate males with abnormally swollen bursa. Suppressor of certain alleles of certain genes.
CB4377 lin-22(n372) pal-2(e2260) IV; him-5(e1490) V; lin-32(e1926) X. Hermaphrodites segregating males with abnormal ray lineages. Reference: Hodgkin et al. (1989) Genome, 31, 625-637. doi:10.1139/g89-116.
CB4554 smg-2(e2008) smg-1(e1228) I; him-5(e1490) V. Smg (protruding vulva) hermaphrodites segregating Smg hermaphrodites and Smg (Male abnormal) males. Reference: Hodgkin et al. (1989) PMID: 2583479.
CB4605 mab-9(e2410) II; him-5(e1490) V.
CB5365 tra-3(bn75) IV; him-5(e1490) V. Him. Temperature-sensitive: infertile above 20C. Variably masculinized XX hermaphrodites segregating normal XO males. Stronger XX masculinization than null alleles of tra-3. Reference: Francis et al. (1995) PMID: 7713420.
CB6740 bus-20(e2990) III; him-5(e1490) V. Anatomically normal hermaphrodites and males; Bus (resistant to infection by M. nematophilum); weakly resistant to Leucobacter Verde2; insensitive to Leucobacter Verde1. Reference: J Hodgkin (unpublished).
CB6742 dhs-5(e2992) II; him-5(e1490) V. Bus (resistant to M. nematophilum infection); sensitive to Leucobacter Verde2, hypersensitive to Leucobacter Verde1. Reference: M J Gravato-Nobre, J Hodgkin (unpublished).
CB7109 acs-20(e3031) IV; him-5(e1490) V. Him. Skiddy, bleach-sensitive hermaphrodites and males. Resistant to Leucobacter Verde1. Reference: O'Rourke et al. (in preparation).
CB7148 him-5(e1490) V; bus-8(tm1410) X; eEx763. eEx763 [bus-8(exonU2stop) + sur-5p::GFP]. Pick GFP+ to maintain. Lethal bus-8 mutation rescued by bus-8 transgene defective in 5' exons U1 and U2. Reference: Stroud et al (in preparation).
CB7425 him-5(e1490) V; bus-25(e3094) X. Him. Small, slow-growing, bleach-sensitive; Bus (resistant to M. nematophilum), slightly resistant to Leucobacter Verde2, hypersensitive to Leucobacter Verde1. Reference: Hodgkin et al (in preparation).
CF12 rol-6(e187) II; lin-22(n372) IV; him-5(e1490) V. Rollers. lin-22 and him-5 mutations affect neuroblast formation from epidermal precursor cell V5.
CF250 cat-4(e1141) him-5(e1490) V. Catecholamine abnormal. Throws males.
CF26 lin-22(mu2) IV; him-5(e1490) V. Alae-to-ray transformation similar to that of n372 animals.
CF301 mab-5(e2088) III; unc-31(e169) IV; him-5(e1490) V; muIs9 X. muIs9 [hs-mab-5 + C14G10]. Heat-shock inducible mab-5. C14G10 contains a WT copy of unc-31. muIs9 integrated by gamma irradiation.
CF31 lin-22(mu5) IV; him-5(e1490) V. Alae-to-ray transformation similar to that of n372 animals.
CF311 mab-5(e1239) egl-5(n945) III; him-5(e1490) V.
CF32 lin-1(e1026) IV; him-5(e1490) V. Very slow growth.
CF439 lin-39(n1760) III; dpy-20(e1282) IV; him-5(e1490) V; muIs23. muIs23 [hsp::lin-39 + (pMH86) dpy-20(+)]. Heat-shock inducible lin-39. muIs23 is a spontaneous integrant whose chromosomal location is unknown.
CF491 pry-1(mu38) I; him-5(e1490) V. Very sick, Muv, Scrawny. Extra rays in males in body. Ectopic expression of lin-39, mab-5, egl-5. Cold sensitive - grows better at 25C.