Gene Information: ppk-3

Nameppk-3 View on WormBase
Species C. elegans
SequenceVF11C1L.1
Genetic positionX:9.14 +/- 0.111 cM
Genomic positionX: 12968884..12977358

Strains carrying this gene

Strain Genotype Description
AC257 ppk-3(n2668) X. Growth retardation, enlarged vacuoles (late endosomes and lysosomes) in intestine, epidermis, coelomocytes and pharynx. 27% embryonic lethality and 8% post-embryonic lethality.
ML855 +/szT1 [lon-2(e678)] I; ppk-3(mc46)/szT1 X. Heterozygotes are WT and segregate WT, arrested szT1 aneuploids, Lon males, mc46 hemizygotes (WT males) and mc46 homozygotes. mc46 is a deletion that results in homozygotes which show enlarged vacuoles (late endosomes and lysosomes) and lay eggs with enlarged vacuoles that die at different stages of embyronic development.
MT7531 ppk-3(n2835) X. n2835 animals show enlarged vacuoles in intestine, epidermis, coelomocytes and pharynx.
VC786 +/szT1 [lon-2(e678)] I; ppk-3(ok1150)/szT1 X. VF11C1L.1. Homozygous sterile deletion chromosome balanced by lon-2-marked translocation. Heterozygotes are WT, and segregate WT, arrested szT1 aneuploids, Lon-2 males, ok1150 hemizygotes (WT males) and ok1150 homozygotes (usually sterile, sometimes Dpyish, may produce a few progeny). Pick WT and check for correct segregation of progeny to maintain. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807