Gene Information: unc-13

Nameunc-13 View on WormBase
Species C. elegans
SequenceZK524.2
Genetic positionI:2.07 +/- 0.004 cM
Genomic positionI: 7422785..7454116

Strains carrying this gene

Strain Genotype Description
EU459 unc-13(e1091) mom-5(zu193)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III; him-8(ec56) IV. Heterozygotes are WT and segregate WT and Uncs. The Uncs have a non-conditional maternal-effect embryonic lethal phenotype: the E blastomere adopts MS fate in about 5% of mutant embryos. The Uncs are 100% penetrant for embyronic lethality and morphogenesis defects.
EU707 air-2(or207) unc-13(e51) I. Temperature sensitive. Grow at permissive temperature of 15C. Fully penetrant cytokinesis defect at the restrictive temperature of 25C. Semi-dominant Unc.
GS305 evl-17(ar94)/dpy-5(e61) unc-13(e51) I. Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS307 dpy-5(e61) cye-1(ar95)/unc-13(e51) I. Heterozygotes are WT and segregate WT, Uncs and Sterile Dpys which have an everted vulva. ar95 previously called evl-10(ar95). See also WBPaper00004382. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS454 evl-9(ar121)/dpy-5(e61) unc-13(e51) I. Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
HR75 mei-1(b284) unc-29(e1072)/mei-1(ct46) unc-13(e1091) I. Heterozygotes are WT. ct46 is a dominant, temperature sensitive maternal effect lethal. ct46 homozygotes are viable and fertile at 15C. b284 is a non-conditional, recessive maternal effect lethal. Heterozygotes give more viable progeny at 15C than 25C.
JK1403 fog-3(q470)/unc-13(e1091) lin-11(n566) I. Heterozygotes are WT and segregate WT, Unc Egls and females. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1466 gld-1(q485)/dpy-5(e61) unc-13(e51) I. Heterozygotes are WT and segregate WT, DpyUncs and steriles with a tumorous germline. Pick WT to maintain. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1545 ces-1(n703) qDf8/unc-13(e1091) lin-11(n566) I. Heterozygotes are Ces and segregate VulUncs and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1547 ces-1(n703) qDf10/unc-13(e1091) lin-11(n566) I. Heterozgotes are Ces and segregate VulUncs and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1548 ces-1(n703) qDf11/unc-13(e1091) lin-11(n566) I. Heterozygotes are Ces and segregate Ces, UncVul and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1550 ces-1(n703) qDf12/unc-13(e1091) lin-11(n566) I. Heterozygotes are Ces and segregate VulUnc and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1556 ces-1(n703) qDf14/unc-13(e1091) lin-11(n566) I. Heterozygotes are Ces and segregate Ces, UncVul and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1557 ces-1(n703) qDf13/unc-13(e1091) lin-11(n566) I. Heterozygotes are Ces and segregate VulUncs and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1573 ces-1(n703) qDf6/dpy-14(e188) unc-13(e51) I. Heterozygotes are Ces and grow very slowly and are often sterile. They segregate very early larval lethals, sickly DpyUncs and more hets. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1743 gld-2(q497)/dpy-5(e61) unc-13(e51) I. Heterozygotes are WT and segregate WT, DpyUncs and Steriles. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK2208 gld-2(dx40)/dpy-5(e61) unc-13(e51) I. Segregates wild-type hets, Ste dx40 homozygotes, and Dpy Uncs. Maintain by picking wild-type and checking for correct segregation. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JM69 dpy-5(e61) unc-13(e1091)/szT1 [lon-2(e678)] I; elt-2(ca15)/szT1 X. Heterozygotes are WT and segregate WT, Lon males and dead eggs.
KR1037 unc-13(e51)/hT1 I; dpy-11(e224)/hT1 [unc-42(e270)] V. Pick wild-type to maintain. Segregates wild-type, Dpy Unc, arrested hT1 homozygotes, and dead eggs. Reference: McKim KS, et al. Genetics. 1988 Dec;120(4):987-1001.
KR1054 dpy-5(e61) unc-13(e450)/hT1 I; +/hT1 [unc-42(e270)] V. Pick wild-type to maintain. Segregates wild-type, Dpy Unc, arrested hT1 homozygotes, and dead eggs. Reference: McKim KS, et al. Genetics. 1988 Dec;120(4):987-1001. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1115 dpy-5(e61) unc-13(e450) hDf9/szT1 [lon-2(e678)] I; +/szT1 X. Wild-type phenotype, Him. Segregates wild-type, Lon-2 males and two classes of arrested embryos (dpy-5 unc-13 hDf9 homozygotes and szT1 aneuploids). Lon males are fertile, carrying hDf9 and both szT1 half translocations (arising by meiotic nondisjunction of normal X chromosome). Maintain by picking wild-type and checking for correct segregation of progeny. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1233 hDf8/dpy-5(e61) unc-13(e450) I. Slow-growing wild-type, Him. Segregates WT, DpyUnc, WT males and dead eggs (hDf8 homozygotes). Heterozygotes also exhibit low-penetrance vulval blips; these may be more pronounced, present at higher frequency and accompanied at times by tail blips upon recovery from starvation. hDf8 dominantly suppresses recombination from around unc-13 at least to dpy-5, and possibly to the left end of chromosome I. Maintain by picking WT and checking for correct segregation of progeny. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1315 let-626(h676) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in late larval development.
KR1319 dpy-5(e61) nars-1(h680) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs. h680 arrests as an early larva. Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR1327 let-635(h688) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/late larval development.
KR1328 let-636(h689) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1329 let-520(h690) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Unc strain which throws DpyUncLet. Late larval arrest (L4). Maintain by picking Unc non-Dpy.
KR1331 let-544(h692) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Unc strain which throws Unc and DpyUnc (animals which have lost the Dp). DpyUncs arrest as adults. Maintain by picking Unc.
KR1334 let-610(h695) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h695 arrests as a sterile adult). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1335 let-633(h696) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are Dpy Unc and arrest in early larval development.
KR1338 let-501(h714) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1339 dpy-5(e61) let-532(h715) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are lethal DpyUncs.
KR1341 let-637(h700) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid/late larval development.
KR1345 let-521(h704) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Unc strain which throws Unc and DpyUncs which arrest late larval (L4). Maintain by picking Unc.
KR1346 let-579(h705) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid larval development.
KR1347 dpy-5(e61) ncbp-1(h706) unc-13(e450) I; sDp2 (I;f). Unc strain which throws Unc and DpyUncs which arrest as early larvae (which live 2 weeks). Maintain by picking Unc.
KR1350 let-580(h709) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in egg/early larval development.
KR1355 let-114(h716) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/mid larval development.
KR1366 unc-11(h725) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid larval development.
KR1367 let-582(h726) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1371 let-515(h730) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1374 dpy-5(e61) let-502(h733) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs. Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1376 dpy-5(e61) let-522(h735) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h735 arrests as an early larva). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1379 let-583(h738) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/mid larval development.
KR1381 let-510(h740) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1384 let-584(h743) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest as Sterile adults.
KR1392 dpy-5(e61) let-523(h751) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs. h751 arrests as an early larva. Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR1393 dpy-5(e61) let-513(h752) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h752 arrests as a sterile adult). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1394 dpy-5(e61) let-514(h753) unc-13(e450) I; sDp2 (I;f). Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h753 arrests as an early larva). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1396 let-511(h755) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.